USE OF 4-GALACTOSYL-XYLOSE IN HUMANS FOR THE IN VIVO EVALUATION OF INTESTINAL LACTASE AS A NON-INVASIVE DIAGNOSTIC TEST OF THE DEFICIENCY OF SAID ENZYME
The invention relates to the use in humans of a method which is based on the use of 4-galactosyl-xylose and which involves an alternative technique to evaluate xylose in urine. The method consists of measuring the concentration of xylose in the blood following the oral administration of 4-galactosyl...
Gespeichert in:
| Hauptverfasser: | , |
|---|---|
| Format: | Patent |
| Sprache: | eng ; fre ; ger |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | FERNANDEZ MAYORALAS ALVAREZ, ALFONSO ARAGON REYES, JUAN JOSE |
| description | The invention relates to the use in humans of a method which is based on the use of 4-galactosyl-xylose and which involves an alternative technique to evaluate xylose in urine. The method consists of measuring the concentration of xylose in the blood following the oral administration of 4-galactosyl-xylose to the patient, the use of said method being even more suitable in the case of newborns. The invention also relates to the technology used for the in vivo evaluation of intestinal lactase activity, by way of a non-invasive test for the diagnosis of a deficiency of said enzyme, which consists of directly evaluating the overall activity of the enzyme in the individual and not in assessing the consequences of said deficiency. The inventive method does not require specialized equipment, does not cause any obvious discomfort to patients with a lactase deficiency and is extremely reliable, thereby eliminating the inconveniences of currently used diagnostic tests. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_EP1553188A1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>EP1553188A1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_EP1553188A13</originalsourceid><addsrcrecordid>eNqNjEEKwjAQRbtxIeod5gJdlFpwO6TTdiCdiEmDdVOKxJVooR7G49qIB3D14fHeXyfvzhKYCvZpjRqVM7bX6bnXZsEs0HQtioXKnMA1X-LZGyCPukPHRmLL4sg6FtQQL3BJ0QKCGElZPFr2BCVjLWbRFEQ7dvGxpIoVk6g-EotcAsmlb2mbrG7jfQ67324SqMipJg3TcwjzNF7DI7wGOmZFkWeHA2b5H8oHeldBxQ</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>USE OF 4-GALACTOSYL-XYLOSE IN HUMANS FOR THE IN VIVO EVALUATION OF INTESTINAL LACTASE AS A NON-INVASIVE DIAGNOSTIC TEST OF THE DEFICIENCY OF SAID ENZYME</title><source>esp@cenet</source><creator>FERNANDEZ MAYORALAS ALVAREZ, ALFONSO ; ARAGON REYES, JUAN JOSE</creator><creatorcontrib>FERNANDEZ MAYORALAS ALVAREZ, ALFONSO ; ARAGON REYES, JUAN JOSE</creatorcontrib><description>The invention relates to the use in humans of a method which is based on the use of 4-galactosyl-xylose and which involves an alternative technique to evaluate xylose in urine. The method consists of measuring the concentration of xylose in the blood following the oral administration of 4-galactosyl-xylose to the patient, the use of said method being even more suitable in the case of newborns. The invention also relates to the technology used for the in vivo evaluation of intestinal lactase activity, by way of a non-invasive test for the diagnosis of a deficiency of said enzyme, which consists of directly evaluating the overall activity of the enzyme in the individual and not in assessing the consequences of said deficiency. The inventive method does not require specialized equipment, does not cause any obvious discomfort to patients with a lactase deficiency and is extremely reliable, thereby eliminating the inconveniences of currently used diagnostic tests.</description><edition>7</edition><language>eng ; fre ; ger</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS OR TEST PAPERS THEREFOR ; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ; ENZYMOLOGY ; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES ; MEASURING ; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS ; METALLURGY ; MICROBIOLOGY ; MUTATION OR GENETIC ENGINEERING ; PHYSICS ; PROCESSES OF PREPARING SUCH COMPOSITIONS ; SPIRITS ; TESTING ; VINEGAR ; WINE</subject><creationdate>2005</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20050713&DB=EPODOC&CC=EP&NR=1553188A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25563,76318</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20050713&DB=EPODOC&CC=EP&NR=1553188A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>FERNANDEZ MAYORALAS ALVAREZ, ALFONSO</creatorcontrib><creatorcontrib>ARAGON REYES, JUAN JOSE</creatorcontrib><title>USE OF 4-GALACTOSYL-XYLOSE IN HUMANS FOR THE IN VIVO EVALUATION OF INTESTINAL LACTASE AS A NON-INVASIVE DIAGNOSTIC TEST OF THE DEFICIENCY OF SAID ENZYME</title><description>The invention relates to the use in humans of a method which is based on the use of 4-galactosyl-xylose and which involves an alternative technique to evaluate xylose in urine. The method consists of measuring the concentration of xylose in the blood following the oral administration of 4-galactosyl-xylose to the patient, the use of said method being even more suitable in the case of newborns. The invention also relates to the technology used for the in vivo evaluation of intestinal lactase activity, by way of a non-invasive test for the diagnosis of a deficiency of said enzyme, which consists of directly evaluating the overall activity of the enzyme in the individual and not in assessing the consequences of said deficiency. The inventive method does not require specialized equipment, does not cause any obvious discomfort to patients with a lactase deficiency and is extremely reliable, thereby eliminating the inconveniences of currently used diagnostic tests.</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS OR TEST PAPERS THEREFOR</subject><subject>CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES</subject><subject>ENZYMOLOGY</subject><subject>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</subject><subject>MEASURING</subject><subject>MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>PHYSICS</subject><subject>PROCESSES OF PREPARING SUCH COMPOSITIONS</subject><subject>SPIRITS</subject><subject>TESTING</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2005</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjEEKwjAQRbtxIeod5gJdlFpwO6TTdiCdiEmDdVOKxJVooR7G49qIB3D14fHeXyfvzhKYCvZpjRqVM7bX6bnXZsEs0HQtioXKnMA1X-LZGyCPukPHRmLL4sg6FtQQL3BJ0QKCGElZPFr2BCVjLWbRFEQ7dvGxpIoVk6g-EotcAsmlb2mbrG7jfQ67324SqMipJg3TcwjzNF7DI7wGOmZFkWeHA2b5H8oHeldBxQ</recordid><startdate>20050713</startdate><enddate>20050713</enddate><creator>FERNANDEZ MAYORALAS ALVAREZ, ALFONSO</creator><creator>ARAGON REYES, JUAN JOSE</creator><scope>EVB</scope></search><sort><creationdate>20050713</creationdate><title>USE OF 4-GALACTOSYL-XYLOSE IN HUMANS FOR THE IN VIVO EVALUATION OF INTESTINAL LACTASE AS A NON-INVASIVE DIAGNOSTIC TEST OF THE DEFICIENCY OF SAID ENZYME</title><author>FERNANDEZ MAYORALAS ALVAREZ, ALFONSO ; ARAGON REYES, JUAN JOSE</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_EP1553188A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre ; ger</language><creationdate>2005</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS OR TEST PAPERS THEREFOR</topic><topic>CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES</topic><topic>ENZYMOLOGY</topic><topic>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</topic><topic>MEASURING</topic><topic>MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>PHYSICS</topic><topic>PROCESSES OF PREPARING SUCH COMPOSITIONS</topic><topic>SPIRITS</topic><topic>TESTING</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>FERNANDEZ MAYORALAS ALVAREZ, ALFONSO</creatorcontrib><creatorcontrib>ARAGON REYES, JUAN JOSE</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>FERNANDEZ MAYORALAS ALVAREZ, ALFONSO</au><au>ARAGON REYES, JUAN JOSE</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>USE OF 4-GALACTOSYL-XYLOSE IN HUMANS FOR THE IN VIVO EVALUATION OF INTESTINAL LACTASE AS A NON-INVASIVE DIAGNOSTIC TEST OF THE DEFICIENCY OF SAID ENZYME</title><date>2005-07-13</date><risdate>2005</risdate><abstract>The invention relates to the use in humans of a method which is based on the use of 4-galactosyl-xylose and which involves an alternative technique to evaluate xylose in urine. The method consists of measuring the concentration of xylose in the blood following the oral administration of 4-galactosyl-xylose to the patient, the use of said method being even more suitable in the case of newborns. The invention also relates to the technology used for the in vivo evaluation of intestinal lactase activity, by way of a non-invasive test for the diagnosis of a deficiency of said enzyme, which consists of directly evaluating the overall activity of the enzyme in the individual and not in assessing the consequences of said deficiency. The inventive method does not require specialized equipment, does not cause any obvious discomfort to patients with a lactase deficiency and is extremely reliable, thereby eliminating the inconveniences of currently used diagnostic tests.</abstract><edition>7</edition><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng ; fre ; ger |
| recordid | cdi_epo_espacenet_EP1553188A1 |
| source | esp@cenet |
| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ENZYMOLOGY INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING PHYSICS PROCESSES OF PREPARING SUCH COMPOSITIONS SPIRITS TESTING VINEGAR WINE |
| title | USE OF 4-GALACTOSYL-XYLOSE IN HUMANS FOR THE IN VIVO EVALUATION OF INTESTINAL LACTASE AS A NON-INVASIVE DIAGNOSTIC TEST OF THE DEFICIENCY OF SAID ENZYME |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-13T00%3A23%3A34IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=FERNANDEZ%20MAYORALAS%20ALVAREZ,%20ALFONSO&rft.date=2005-07-13&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EEP1553188A1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |