Use of heparinases to decrease inflammatory responses

Heparinase enzymes can be used as a medical treatment to reduce localized inflammatory responses. Treatment of activated endothelium with heparinase inhibits leukocyte rolling, adhesion and extravasation. Most of the heparin and heparan sulfate on endothelial cell surfaces and in basement membranes...

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Hauptverfasser: GROUIX , BRIGETTE, CAUCHON, ELIZABETH, HSIA, ARIANE, BENNETT, D, CLARK, FINK, DOMINIKQUE, ZIMEMERMAN, JOSEPH, DANAGHER, PAMELA
Format: Patent
Sprache:eng ; fre ; ger
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