DIAMINO-PYRIMIDINES AND THEIR USE AS ANGIOGENESIS INHIBITORS

Benzimidazole derivatives, which are useful as TIE-2 and/or VEGFR-2 inhibitors are described herein. The described invention also includes methods of making such benzimidazole derivatives as well as methods of using the same in the treatment of hyperproliferative diseases.

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Bibliographische Detailangaben
Hauptverfasser:	CHAMBERLAIN, STANLEY, DAWES, SEMONES, MARCUS, EMERSON, HOLLY, KATHLEEN, NAILOR, KRISTEN, ELIZABETH, CHEUNG, MUI, JOHNSON, NEIL, W, SAMMOND, DOUGLAS, MCCORD
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Benzimidazole derivatives, which are useful as TIE-2 and/or VEGFR-2 inhibitors are described herein. The described invention also includes methods of making such benzimidazole derivatives as well as methods of using the same in the treatment of hyperproliferative diseases.