CARDIOVASCULAR SAFETY ASSAY

The present invention provides assays and kits for the screening of test compounds for their capability to induce cardiotoxicity in a subject. Said assays and kits are based on the finding that the interaction of astemizole with the HERG potassium channel can be exploited to predict cardiotoxicity o...

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Bibliographische Detailangaben
Hauptverfasser: JANSSEN, CORNELUS, GERARDUS, MARIA, HEYLEN, GODELIEVE, IRMA, CHRISTINE, MARIA, JURZAK, MIREK, VAN ASSOUW, HENRICUS, PETRUS, MARTINUS, MARIA
Format: Patent
Sprache:eng ; fre ; ger
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