VINYL PHENYL DERIVATIVES AS GLK ACTIVATORS

The invention related to novel compounds of Formula (I) or a salt, solvate or prodrug thereof, wherein A, R1, R2, R3, n and m are as described in the specification, useful in the treatment of a disease or condition mediated through glucokinase (GLK), such as type 2 diabetes. The invention also relat...

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Hauptverfasser: HARGREAVES, RODNEY, BRIAN, CAULKETT, PETER, WILLIAM, RODNEY, CURRIE, GORDON, STUART, HAYTER, BARRY, RAYMOND, JAMES, ROGER
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creator HARGREAVES, RODNEY, BRIAN
CAULKETT, PETER, WILLIAM, RODNEY
CURRIE, GORDON, STUART
HAYTER, BARRY, RAYMOND
JAMES, ROGER
description The invention related to novel compounds of Formula (I) or a salt, solvate or prodrug thereof, wherein A, R1, R2, R3, n and m are as described in the specification, useful in the treatment of a disease or condition mediated through glucokinase (GLK), such as type 2 diabetes. The invention also relates to methods for preparing compounds of Formula (I) and their use as medicaments in the treatment of diseases mediated by glucokinase.
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language eng ; fre ; ger
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title VINYL PHENYL DERIVATIVES AS GLK ACTIVATORS
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