HSA-free formulations of interferon-beta
Stabilized pharmaceutical compositions comprising substantially monomeric interferon-beta (IFN-²) and methods useful in their preparation are provided. The compositions comprise the IFN-² solubilised in a low-ionic-strength formulation that maintains the composition at a pH of about 5.0. Methods for...
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| creator | BABUKA, SUSAN TELLERS, MELANIE SHIRLEY, BRET, A CHOE, MINNA CHEN, BAO-LU HORA, MANINDER |
| description | Stabilized pharmaceutical compositions comprising substantially monomeric interferon-beta (IFN-²) and methods useful in their preparation are provided. The compositions comprise the IFN-² solubilised in a low-ionic-strength formulation that maintains the composition at a pH of about 5.0. Methods for preparing these compositions, and for increasing solubility of IFN-² in pharmaceutical compositions, are provided. |
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| language | eng ; fre ; ger |
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| subjects | HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | HSA-free formulations of interferon-beta |
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