PROCESS FOR PRODUCING (3R,5S)-(E)-7- 2-CYCLOPROPYL-4-(4-FLUOROPHENYL)-QUINOLIN-3-YL -3,5-DIHYDROXYHEPT-6-ENIC ACID ESTERS

PROCESS FOR PRODUCING (3R,5S)-(E)-7- 2-CYCLOPROPYL-4-(4-FLUOROPHENYL)-QUINOLIN-3-YL -3,5-DIHYDROXYHEPT-6-ENIC ACID ESTERS

A process for producing a compound represented by the following formula (IV): (wherein R denotes a hydrogen atom, an alkyl group, or an aryl group), comprising reducing a compound selected from the group consisting of: a compound represented by the following formula (I): (wherein R is as defined in...

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Bibliographische Detailangaben
Hauptverfasser: HARA, MARI, TAKUMA, YUKI, HOSOKAWA, AKEMI, WATANABE, NAOYUKI, KATSURADA, MANABU, MATSUMOTO, YOUICHI, KASUGA, YUZO
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
BEER
BIOCHEMISTRY
CHEMISTRY
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
HETEROCYCLIC COMPOUNDS
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
SPIRITS
VINEGAR
WINE
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Beschreibung
Zusammenfassung:A process for producing a compound represented by the following formula (IV): (wherein R denotes a hydrogen atom, an alkyl group, or an aryl group), comprising reducing a compound selected from the group consisting of: a compound represented by the following formula (I): (wherein R is as defined in the formula); a compound represented by the following formula (II): (wherein R is as defined in the formula); and a compound represented by the following formula (III): (wherein R is as defined in the formula), by reacting the compound with a cell of a microorganism and/or a cell preparation thereof capable of stereo-selectively reducing a keto group.