Novel peptide nucleic acids

A novel class of compounds, known as peptide nucleic acids, bind complementary ssDNA and RNA strands more strongly than a corresponding DNA. The peptide nucleic acids generally comprise ligands such as naturally occurring DNA bases attached to a peptide backbone through a suitable linker.

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Bibliographische Detailangaben
Hauptverfasser: BUCHARDT, DORTE, NIELSEN, PETER EIGIL, BERG, ROLF, EGHOLM, MICHAEL
Format: Patent
Sprache:eng ; fre ; ger
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Beschreibung
Zusammenfassung:A novel class of compounds, known as peptide nucleic acids, bind complementary ssDNA and RNA strands more strongly than a corresponding DNA. The peptide nucleic acids generally comprise ligands such as naturally occurring DNA bases attached to a peptide backbone through a suitable linker.