Resolving agents based on amines

The invention relates to a resolving agent consisting of a chiral sulphamic acid derivative of the formula (R1,R2)N-SO3H, wherein R1 and R2, being the same or different, represent a hydrogen atom, an optionally substituted, linear, branched or cyclic alkyl or heteroalkyl group, or an optionally subs...

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Hauptverfasser:	SMITH, ALAN ARTHUR, KUSTER, GEORGE JOHANNES THEODORUS, DAMEN, FRANCISCUS WILHELMUS PETRUS
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS APPARATUS THEREFOR CHEMISTRY GENERAL METHODS OF ORGANIC CHEMISTRY METALLURGY ORGANIC CHEMISTRY
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creator	SMITH, ALAN ARTHUR KUSTER, GEORGE JOHANNES THEODORUS DAMEN, FRANCISCUS WILHELMUS PETRUS
description	The invention relates to a resolving agent consisting of a chiral sulphamic acid derivative of the formula (R1,R2)N-SO3H, wherein R1 and R2, being the same or different, represent a hydrogen atom, an optionally substituted, linear, branched or cyclic alkyl or heteroalkyl group, or an optionally substituted aromatic or heteroaromatic group, provided that at least one of the R1 and R2 groups is chiral. The invention also relates to a process for the resolution of a mixture of enantiomers using said resolving agent and to a process for the preparation of a chiral sulphamic acid derivative wherein an amine of the formula (R1,R2)N-H, wherein R1 and R2 are as defined above, is reacted with a suitable reagent to obtain said chiral sulphamic acid.
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The invention also relates to a process for the resolution of a mixture of enantiomers using said resolving agent and to a process for the preparation of a chiral sulphamic acid derivative wherein an amine of the formula (R1,R2)N-H, wherein R1 and R2 are as defined above, is reacted with a suitable reagent to obtain said chiral sulphamic acid.</description><edition>7</edition><language>eng ; fre ; ger</language><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS ; APPARATUS THEREFOR ; CHEMISTRY ; GENERAL METHODS OF ORGANIC CHEMISTRY ; METALLURGY ; ORGANIC CHEMISTRY</subject><creationdate>2002</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20021211&DB=EPODOC&CC=EP&NR=1264814A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76516</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20021211&DB=EPODOC&CC=EP&NR=1264814A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>SMITH, ALAN ARTHUR</creatorcontrib><creatorcontrib>KUSTER, GEORGE JOHANNES THEODORUS</creatorcontrib><creatorcontrib>DAMEN, FRANCISCUS WILHELMUS PETRUS</creatorcontrib><title>Resolving agents based on amines</title><description>The invention relates to a resolving agent consisting of a chiral sulphamic acid derivative of the formula (R1,R2)N-SO3H, wherein R1 and R2, being the same or different, represent a hydrogen atom, an optionally substituted, linear, branched or cyclic alkyl or heteroalkyl group, or an optionally substituted aromatic or heteroaromatic group, provided that at least one of the R1 and R2 groups is chiral. The invention also relates to a process for the resolution of a mixture of enantiomers using said resolving agent and to a process for the preparation of a chiral sulphamic acid derivative wherein an amine of the formula (R1,R2)N-H, wherein R1 and R2 are as defined above, is reacted with a suitable reagent to obtain said chiral sulphamic acid.</description><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS</subject><subject>APPARATUS THEREFOR</subject><subject>CHEMISTRY</subject><subject>GENERAL METHODS OF ORGANIC CHEMISTRY</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2002</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZFAISi3OzynLzEtXSExPzSspVkhKLE5NUcjPU0jMzcxLLeZhYE1LzClO5YXS3AwKbq4hzh66qQX58anFBYnJqXmpJfGuAYZGZiYWhiaOhsZEKAEAASMktw</recordid><startdate>20021211</startdate><enddate>20021211</enddate><creator>SMITH, ALAN ARTHUR</creator><creator>KUSTER, GEORGE JOHANNES THEODORUS</creator><creator>DAMEN, FRANCISCUS WILHELMUS PETRUS</creator><scope>EVB</scope></search><sort><creationdate>20021211</creationdate><title>Resolving agents based on amines</title><author>SMITH, ALAN ARTHUR ; KUSTER, GEORGE JOHANNES THEODORUS ; DAMEN, FRANCISCUS WILHELMUS PETRUS</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_EP1264814A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre ; ger</language><creationdate>2002</creationdate><topic>ACYCLIC OR CARBOCYCLIC COMPOUNDS</topic><topic>APPARATUS THEREFOR</topic><topic>CHEMISTRY</topic><topic>GENERAL METHODS OF ORGANIC CHEMISTRY</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><toplevel>online_resources</toplevel><creatorcontrib>SMITH, ALAN ARTHUR</creatorcontrib><creatorcontrib>KUSTER, GEORGE JOHANNES THEODORUS</creatorcontrib><creatorcontrib>DAMEN, FRANCISCUS WILHELMUS PETRUS</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>SMITH, ALAN ARTHUR</au><au>KUSTER, GEORGE JOHANNES THEODORUS</au><au>DAMEN, FRANCISCUS WILHELMUS PETRUS</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Resolving agents based on amines</title><date>2002-12-11</date><risdate>2002</risdate><abstract>The invention relates to a resolving agent consisting of a chiral sulphamic acid derivative of the formula (R1,R2)N-SO3H, wherein R1 and R2, being the same or different, represent a hydrogen atom, an optionally substituted, linear, branched or cyclic alkyl or heteroalkyl group, or an optionally substituted aromatic or heteroaromatic group, provided that at least one of the R1 and R2 groups is chiral. 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subjects	ACYCLIC OR CARBOCYCLIC COMPOUNDS APPARATUS THEREFOR CHEMISTRY GENERAL METHODS OF ORGANIC CHEMISTRY METALLURGY ORGANIC CHEMISTRY
title	Resolving agents based on amines
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