PROCESS FOR MAKING GEMINAL BISPHOSPHONATES

The present invention relates to a novel process for making geminal bisphosphonates. The process provides for bisphosphorylation using phosphorus trihalide, phosphorous acid as a reactant/solvent, and a base as an acid acceptor/solvent. The present invention is directed to a process for making gemin...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: CAZER, FREDRICK, DANA, PERRY, GREGORY, EUGENE, BILLINGS, DENNIS, MICHAEL, CRAMER, WILLIAM, DOUGLAS
Format: Patent
Sprache:eng ; fre ; ger
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