DRUG PREPARATION "HISTOCHROME" FOR TREATING ACUTE MYOCARDIAL INFARCTION AND ISCHAEMIC HEART DISEASES

DRUG PREPARATION "HISTOCHROME" FOR TREATING ACUTE MYOCARDIAL INFARCTION AND ISCHAEMIC HEART DISEASES

A pharmaceutical composition is provided, which comprises an aqeous solution containing a mixture of di- and tri-sodium salts of echinochrome in an amount of 0.90 to 1.10 g/ml (Histochrome). It meets the requirements that apply to injectable formulations. Administration of Histochrome reduces by 57%...

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Hauptverfasser: ELYAKOV, GEORGY BORISOVICH, GLEBKO, LUTSIYA IGNATIENNA, MISCHENKO, NATALIYA PETROVNA, FEDOREEV, SERGEI ALEXANDROVICH, MAXIMOV, OLEG BORISOVICH, KOLTSOVA, EVGENIYA ALEXANDROVNA, ARTJUKOV, ALEXANDR ALEXEEVICH, KRASOVSKAYA, NATALIYA PETROVNA
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Sprache:eng ; fre ; ger
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HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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creator ELYAKOV, GEORGY BORISOVICH
GLEBKO, LUTSIYA IGNATIENNA
MISCHENKO, NATALIYA PETROVNA
FEDOREEV, SERGEI ALEXANDROVICH
MAXIMOV, OLEG BORISOVICH
KOLTSOVA, EVGENIYA ALEXANDROVNA
ARTJUKOV, ALEXANDR ALEXEEVICH
KRASOVSKAYA, NATALIYA PETROVNA
description A pharmaceutical composition is provided, which comprises an aqeous solution containing a mixture of di- and tri-sodium salts of echinochrome in an amount of 0.90 to 1.10 g/ml (Histochrome). It meets the requirements that apply to injectable formulations. Administration of Histochrome reduces by 57% the necrosis zone in patients with acute myocardial infarction, restores the contractility of the left ventricle, reduces the incidence of reperfusion-induced ventricular arrhythmias and exerts an antiarrhythmogenic effect. Histochrome suppresses the aggregation of erythrocytes and thrombocytes, produces a beneficial effect on the clinical course of the disease, reduces the incidence of complications and lethal outcomes in cases of acute myocardial infarction. It is well tolerated by patients.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title DRUG PREPARATION "HISTOCHROME" FOR TREATING ACUTE MYOCARDIAL INFARCTION AND ISCHAEMIC HEART DISEASES
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