A SCALABLE METHOD FOR THE ISOLATION OF ANTI-HIV AGENTS FROM THE TROPICAL PLANT $i(CALOPHYLLUM)

An efficient and scalable method is reported for the isolation of costatolide (2), an HIV-1-specific nonnucleoside reverse transcriptase inhibitor (NNRTI), from the latex of Calophyllum plants such as C. teysmannii var. inophylloide. An overall yield of 10.6% of costatolide, with a purity of 96%, wa...

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Hauptverfasser:	XU, ZE-QI, ANDERSON, HERBERT, M, FLAVIN, MICHAEL, T, JENTA, TUAH, R, LIN, YUH-MEEI, WILLIAMS, MICHAEL, J
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY
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