Urokinase-type plasminogen activator receptor

The use of substances capable of preventing the binding of a receptor binding form of u-PA to a u-PA receptor (u-PAR) in a mammal and thereby preventing u-PA from converting plasminogen into plasmin thereby preventing cell surface plasminogen activation which is believed to play an important role in...

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Bibliographische Detailangaben
Hauptverfasser:	MOELLER, LISBETH BIRK, APPELLA, ETTORE, SALONEN, EEVA-MARJATTE, POELLAENEN, JARI, LUND, LEIF ROEGE, PLOUG, MICHAEL, VAHERI, ANTTI, ELLIS, VINCENT, CUBELLIS, MARIA VITTORIA, ROLDAN, ANN LOURING, BLASI, FRANCESCO, TAPIOVAARA, HANNELE, SCHLEUNING, WOLF DIETER, STEPHENS, ROSS W, BEHRENDT, NIELS, PYKE, CHARLES, ROENNE, EBBE, KRISTESEN, PETER, DANO, KELD, MASUCCI, MARIA TERESA
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES OF PREPARING SUCH COMPOSITIONS PROCESSES USING MICROORGANISMS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	The use of substances capable of preventing the binding of a receptor binding form of u-PA to a u-PA receptor (u-PAR) in a mammal and thereby preventing u-PA from converting plasminogen into plasmin thereby preventing cell surface plasminogen activation which is believed to play an important role in tissue remodelling, particularly during cancer invasion for preparing a composition for preventing or counteracting localized proteolytic activity in a mammal, in particular a human.