USE OF 7-ALKYLIDENE CEPHALOSPORINS TO INHIBIT ELASTASE ACTIVITY

The present invention relates to the use of 7-alkylidene derivatives of cephalosporin esters, such as sulfides, sulfoxides, and sulfones, as inhibitors of human leukocyte elastase. These materials are therefore useful as anti-inflammatory and anti-degenerative agents.

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Hauptverfasser: RAO, AKIREDDY, SRINIVASA, BUYNAK, JOHN, D, ADAM, GREG, C
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creator RAO, AKIREDDY, SRINIVASA
BUYNAK, JOHN, D
ADAM, GREG, C
description The present invention relates to the use of 7-alkylidene derivatives of cephalosporin esters, such as sulfides, sulfoxides, and sulfones, as inhibitors of human leukocyte elastase. These materials are therefore useful as anti-inflammatory and anti-degenerative agents.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title USE OF 7-ALKYLIDENE CEPHALOSPORINS TO INHIBIT ELASTASE ACTIVITY
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