INHIBITION OF INVASIVE REMODELLING

INHIBITION OF INVASIVE REMODELLING

The invention pertains to novel methods for preventing or arresting invasive remodelling in mammals by utilising a combination of in vivo inhibition of plasmin and in vivo inhibition of certain other proteolytic enzymes, notably metalloproteases. The method can e.g. be used as a novel alternative to...

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Hauptverfasser: NIELSEN, JOHN ROEMER, DANOE, KELD, LUND, LEIF ROEGE, STEPHENS, ROSS, SOLBERG, HELENE, HOLST-HANSEN, CLAUS, BRUENNER, NILS
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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creator NIELSEN, JOHN ROEMER
DANOE, KELD
LUND, LEIF ROEGE
STEPHENS, ROSS
SOLBERG, HELENE
HOLST-HANSEN, CLAUS
BRUENNER, NILS
description The invention pertains to novel methods for preventing or arresting invasive remodelling in mammals by utilising a combination of in vivo inhibition of plasmin and in vivo inhibition of certain other proteolytic enzymes, notably metalloproteases. The method can e.g. be used as a novel alternative to current methods of contraception as well as antifungal and antibacterial treatment. The preferred embodiments relate to treatment and prevention of neoplastic diseases by use of these combinations. Further, the invention relates to novel compositions which comprises a plasmin inhibitor in admixture with an inhibitor of another proteolytic enzyme, preferably an inhibitor of a metalloprotease.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title INHIBITION OF INVASIVE REMODELLING
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