METHOD FOR SEARCHING FOR PEPTIDES AND PROCESS FOR PRODUCING COMPOUNDS

METHOD FOR SEARCHING FOR PEPTIDES AND PROCESS FOR PRODUCING COMPOUNDS

Peptides having a higher physiological activity are screened by the steps of (a) synthesizing an optional number of peptides having different arbitrary amino acid sequences; (b) assaying the peptides synthesized in step (a) for their physiological activities to select an optional number of peptides...

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Hauptverfasser: YOKOBAYASHI, YOUHEI, KARUBE, MASAO
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Sprache:eng ; fre ; ger
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CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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KARUBE, MASAO
description Peptides having a higher physiological activity are screened by the steps of (a) synthesizing an optional number of peptides having different arbitrary amino acid sequences; (b) assaying the peptides synthesized in step (a) for their physiological activities to select an optional number of peptides having higher physiological activities; (c) synthesizing peptides having amino acid sequences obtained by genetic algorithm processing of the amino acid sequences of the peptides selected in step (b); and, (d) repeating step (b) and step (c), an optional number of times, for the peptides obtained in step (c). In genetic algorithms, each amino acid is represented by one notation and amino acid sequence of a peptide by the representation is used as a genome.
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subjects CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
title METHOD FOR SEARCHING FOR PEPTIDES AND PROCESS FOR PRODUCING COMPOUNDS
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