USE OF SYNERGISTIC COMPOSITIONS OF IL-12 AND IFN-ALPHA FOR THE TREATMENT OF INFECTIOUS DISEASES

USE OF SYNERGISTIC COMPOSITIONS OF IL-12 AND IFN-ALPHA FOR THE TREATMENT OF INFECTIOUS DISEASES

The present invention provides a combination of IL-12 and IFN alpha together with a pharmaceutically acceptable carrier useful for treatment and prophylaxis of infectious diseases, preferably chronic infectious diseases and more preferably viral infections, e.g. HSV, HIV, Hepatitis B, Hepatitis C, p...

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Hauptverfasser: ALBER, GOTTFRIED, PALMER, KATHRIN, MATTNER, FRANK, ALBERT, ROGERSON, JANE, ANDRE, LOUISE, CARR, JACQUELINE, ANNE, MULQUEEN, MICHAEL, JOHN
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Sprache:eng ; fre ; ger
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HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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creator ALBER, GOTTFRIED
PALMER, KATHRIN
MATTNER, FRANK, ALBERT
ROGERSON, JANE, ANDRE, LOUISE
CARR, JACQUELINE, ANNE
MULQUEEN, MICHAEL, JOHN
description The present invention provides a combination of IL-12 and IFN alpha together with a pharmaceutically acceptable carrier useful for treatment and prophylaxis of infectious diseases, preferably chronic infectious diseases and more preferably viral infections, e.g. HSV, HIV, Hepatitis B, Hepatitis C, papilloma etc., bacterial infections, e.g. tuberculosis, salmonellosis, listeriosis, etc., and parasite infections, e.g. malaria, leishmaniasis, and schistosomiasis. These compositions are characterized by the synergistic interaction of IL-12 and IFN alpha . The present invention also provides the use of the above combination for the treatment and prophylaxis of infectious diseases.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title USE OF SYNERGISTIC COMPOSITIONS OF IL-12 AND IFN-ALPHA FOR THE TREATMENT OF INFECTIOUS DISEASES
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