Actinoplanes sp. biosynthetic pathway genes for acarbose, isolation and use
Die Erfindung betrifft Acarbose-Biosynthesegene aus Actinomyceten, vorwiegend aus Actinoplanes sp. SE 50/110 und seiner Mutanten, ein Verfahren zur Isolierung von Acarbose-Biosynthesegenen aus Actinomyceten mittels einer Gensonde, die von hochkonservierten Proteinbereichen bekannter dTDP-Glucose-Deh...
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| creator | PIEPERSBERG, WOLFGANG, DR DISTLER, JUERGEN CRUEGER, ANNELIESE STRATMANN, ANSGAR |
| description | Die Erfindung betrifft Acarbose-Biosynthesegene aus Actinomyceten, vorwiegend aus Actinoplanes sp. SE 50/110 und seiner Mutanten, ein Verfahren zur Isolierung von Acarbose-Biosynthesegenen aus Actinomyceten mittels einer Gensonde, die von hochkonservierten Proteinbereichen bekannter dTDP-Glucose-Dehydratase-Enzyme abgeleitet wurde, für das Auffinden der Gene acbA (kodierend für dTDP-Glucose synthase), acbB (kodierend für dTDP-Glucose dehydratase) und acbC (kodierend für eine Cyclase, z.T. identisch mit AroB, bakteriellen 3-Dehydrochinasäure Synthasen) oder einem oder mehreren Acarbose-Biosynthesegenen aus Actinoplanes sp., sowie die Verwendung der Acarbose-Biosynthesegene.
DNA (I) with a 2219 bp sequence given in the specification is new. Also claimed are: (1) functional variants of (I); (2) vectors contg. (I) or its variants; (3) microorganisms transformed with the vectors of (2); (3) an amino acid sequence with the above 2219 bp sequence (sic); and (4) proteins contg. at least part of the amino acid sequence of (3). |
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DNA (I) with a 2219 bp sequence given in the specification is new. Also claimed are: (1) functional variants of (I); (2) vectors contg. (I) or its variants; (3) microorganisms transformed with the vectors of (2); (3) an amino acid sequence with the above 2219 bp sequence (sic); and (4) proteins contg. at least part of the amino acid sequence of (3).</description><edition>6</edition><language>eng ; fre ; ger</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; DERIVATIVES THEREOF ; ENZYMOLOGY ; FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; NUCLEIC ACIDS ; NUCLEOSIDES ; NUCLEOTIDES ; ORGANIC CHEMISTRY ; PEPTIDES ; PROCESSES USING MICROORGANISMS ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPIRITS ; SUGARS ; VINEGAR ; WINE</subject><creationdate>1996</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19960904&DB=EPODOC&CC=EP&NR=0730029A2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76289</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19960904&DB=EPODOC&CC=EP&NR=0730029A2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>PIEPERSBERG, WOLFGANG, DR</creatorcontrib><creatorcontrib>DISTLER, JUERGEN</creatorcontrib><creatorcontrib>CRUEGER, ANNELIESE</creatorcontrib><creatorcontrib>STRATMANN, ANSGAR</creatorcontrib><title>Actinoplanes sp. biosynthetic pathway genes for acarbose, isolation and use</title><description>Die Erfindung betrifft Acarbose-Biosynthesegene aus Actinomyceten, vorwiegend aus Actinoplanes sp. SE 50/110 und seiner Mutanten, ein Verfahren zur Isolierung von Acarbose-Biosynthesegenen aus Actinomyceten mittels einer Gensonde, die von hochkonservierten Proteinbereichen bekannter dTDP-Glucose-Dehydratase-Enzyme abgeleitet wurde, für das Auffinden der Gene acbA (kodierend für dTDP-Glucose synthase), acbB (kodierend für dTDP-Glucose dehydratase) und acbC (kodierend für eine Cyclase, z.T. identisch mit AroB, bakteriellen 3-Dehydrochinasäure Synthasen) oder einem oder mehreren Acarbose-Biosynthesegenen aus Actinoplanes sp., sowie die Verwendung der Acarbose-Biosynthesegene.
DNA (I) with a 2219 bp sequence given in the specification is new. Also claimed are: (1) functional variants of (I); (2) vectors contg. (I) or its variants; (3) microorganisms transformed with the vectors of (2); (3) an amino acid sequence with the above 2219 bp sequence (sic); and (4) proteins contg. at least part of the amino acid sequence of (3).</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS THEREOF</subject><subject>CULTURE MEDIA</subject><subject>DERIVATIVES THEREOF</subject><subject>ENZYMOLOGY</subject><subject>FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>NUCLEIC ACIDS</subject><subject>NUCLEOSIDES</subject><subject>NUCLEOTIDES</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PROCESSES USING MICROORGANISMS</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPIRITS</subject><subject>SUGARS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1996</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjDEKwkAQAK-xkOgf9gFGjqQQyxAigo2FfdicG3Nw3C7ZFcnvVfABVlPMMGt3aYLFzJIwk4LKHobIumSbyGIAQZteuMCDvnrkGTDgPLDSDqJyQoucAfMdnkobtxoxKW1_LBycult7Lkm4JxUMn4v13dUfau-rY1PVfyRvAbA1Ag</recordid><startdate>19960904</startdate><enddate>19960904</enddate><creator>PIEPERSBERG, WOLFGANG, DR</creator><creator>DISTLER, JUERGEN</creator><creator>CRUEGER, ANNELIESE</creator><creator>STRATMANN, ANSGAR</creator><scope>EVB</scope></search><sort><creationdate>19960904</creationdate><title>Actinoplanes sp. biosynthetic pathway genes for acarbose, isolation and use</title><author>PIEPERSBERG, WOLFGANG, DR ; DISTLER, JUERGEN ; CRUEGER, ANNELIESE ; STRATMANN, ANSGAR</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_EP0730029A23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre ; ger</language><creationdate>1996</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS THEREOF</topic><topic>CULTURE MEDIA</topic><topic>DERIVATIVES THEREOF</topic><topic>ENZYMOLOGY</topic><topic>FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>NUCLEIC ACIDS</topic><topic>NUCLEOSIDES</topic><topic>NUCLEOTIDES</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PROCESSES USING MICROORGANISMS</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPIRITS</topic><topic>SUGARS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>PIEPERSBERG, WOLFGANG, DR</creatorcontrib><creatorcontrib>DISTLER, JUERGEN</creatorcontrib><creatorcontrib>CRUEGER, ANNELIESE</creatorcontrib><creatorcontrib>STRATMANN, ANSGAR</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>PIEPERSBERG, WOLFGANG, DR</au><au>DISTLER, JUERGEN</au><au>CRUEGER, ANNELIESE</au><au>STRATMANN, ANSGAR</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Actinoplanes sp. biosynthetic pathway genes for acarbose, isolation and use</title><date>1996-09-04</date><risdate>1996</risdate><abstract>Die Erfindung betrifft Acarbose-Biosynthesegene aus Actinomyceten, vorwiegend aus Actinoplanes sp. SE 50/110 und seiner Mutanten, ein Verfahren zur Isolierung von Acarbose-Biosynthesegenen aus Actinomyceten mittels einer Gensonde, die von hochkonservierten Proteinbereichen bekannter dTDP-Glucose-Dehydratase-Enzyme abgeleitet wurde, für das Auffinden der Gene acbA (kodierend für dTDP-Glucose synthase), acbB (kodierend für dTDP-Glucose dehydratase) und acbC (kodierend für eine Cyclase, z.T. identisch mit AroB, bakteriellen 3-Dehydrochinasäure Synthasen) oder einem oder mehreren Acarbose-Biosynthesegenen aus Actinoplanes sp., sowie die Verwendung der Acarbose-Biosynthesegene.
DNA (I) with a 2219 bp sequence given in the specification is new. Also claimed are: (1) functional variants of (I); (2) vectors contg. (I) or its variants; (3) microorganisms transformed with the vectors of (2); (3) an amino acid sequence with the above 2219 bp sequence (sic); and (4) proteins contg. at least part of the amino acid sequence of (3).</abstract><edition>6</edition><oa>free_for_read</oa></addata></record> |
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| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA DERIVATIVES THEREOF ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PEPTIDES PROCESSES USING MICROORGANISMS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS SUGARS VINEGAR WINE |
| title | Actinoplanes sp. biosynthetic pathway genes for acarbose, isolation and use |
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