CYCLOALKYL AMINE BIS-ARYL SQUALENE SYNTHASE INHIBITORS
This invention relates to a class of novel polycyclic compounds containing a cycloalkyl ring having substituted thereon a primary amine and which is further linked or bridged to two mono- and/or bicyclic rings and which reduces levels of serum cholesterol in the body without significantly reducing m...
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| creator | ULLRICH, JOHN, W LEARN, KEITH S KIESOW, TERENCE J SCOTESE, ANTHONY C NEUENSCHWANDER, KENT W DANKULICH, WILLIAM P |
| description | This invention relates to a class of novel polycyclic compounds containing a cycloalkyl ring having substituted thereon a primary amine and which is further linked or bridged to two mono- and/or bicyclic rings and which reduces levels of serum cholesterol in the body without significantly reducing mevalonic metabolite synthesis. This invention relates also to pharmacological compositions and method of treatment for lowering serum cholesterol levels using the compounds of this invention. |
| format | Patent |
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This invention relates also to pharmacological compositions and method of treatment for lowering serum cholesterol levels using the compounds of this invention.</abstract><edition>7</edition><oa>free_for_read</oa></addata></record> |
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| subjects | ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | CYCLOALKYL AMINE BIS-ARYL SQUALENE SYNTHASE INHIBITORS |
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