Long-chain alkylamides of aminoacids and peptides with antiproliferative and antiinflammatory properties
Langkettige unverzweigte Alkylamide der allgemeinen Formel CH3-(CH2)n-NH-R, wobei n = 11 - 20 und R = Aminosäure, deren D- und L-Enantiomeren, Di- und Tripeptide, durch N-Schutzgruppen derivatisierte Formen und endständige Ethylester, sowie deren physiologisch verträgliche Salzformen als pharmazeuti...
Gespeichert in:
| Hauptverfasser: | , , , , , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng ; fre ; ger |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | BERND, MICHAEL GROSSMANN, HEINZ ARP, JUERGEN VOEGELI, R LIEFLAENDER, MANFRED, DR KUTSCHER, BERNHARD ENGEL, JUERGEN KICK, MARIA |
| description | Langkettige unverzweigte Alkylamide der allgemeinen Formel CH3-(CH2)n-NH-R, wobei n = 11 - 20 und R = Aminosäure, deren D- und L-Enantiomeren, Di- und Tripeptide, durch N-Schutzgruppen derivatisierte Formen und endständige Ethylester, sowie deren physiologisch verträgliche Salzformen als pharmazeutische Wirkstoffe mit antiproliferativen und entzündungshemmenden Eigenschaften.
Long chain unbranched alkylamide derivs. of formula (I) and their physiologically acceptable salts which can be used as pharmaceuticals with antiproliferative and anti-inflammatory properties are new. Me(CH2)nNHR (I) n = 11-20; R = amino acid gps., their D- and L-enantiomers, di- and tri-peptides, N-protected forms and terminal ethyl esters. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_EP0670330A1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>EP0670330A1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_EP0670330A13</originalsourceid><addsrcrecordid>eNqNjEEKwjAQRbtxIeod5gKFSEDXIi0uXLhwX4ZkYgfTJCSD0tsbiwdw9T_vP_66Ga8xPFozIgdA_5w9TmypQHRQW4ho2BbAYCFRkmV6s4yVCKccPTvKKPyixflSDq6eTCgxz1CVRFmYyrZZOfSFdr_cNNB39_OlpRQHKgkNBZKhu6nDUWmtTnv9h_IB_bNBDg</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Long-chain alkylamides of aminoacids and peptides with antiproliferative and antiinflammatory properties</title><source>esp@cenet</source><creator>BERND, MICHAEL ; GROSSMANN, HEINZ ; ARP, JUERGEN ; VOEGELI, R ; LIEFLAENDER, MANFRED, DR ; KUTSCHER, BERNHARD ; ENGEL, JUERGEN ; KICK, MARIA</creator><creatorcontrib>BERND, MICHAEL ; GROSSMANN, HEINZ ; ARP, JUERGEN ; VOEGELI, R ; LIEFLAENDER, MANFRED, DR ; KUTSCHER, BERNHARD ; ENGEL, JUERGEN ; KICK, MARIA</creatorcontrib><description>Langkettige unverzweigte Alkylamide der allgemeinen Formel CH3-(CH2)n-NH-R, wobei n = 11 - 20 und R = Aminosäure, deren D- und L-Enantiomeren, Di- und Tripeptide, durch N-Schutzgruppen derivatisierte Formen und endständige Ethylester, sowie deren physiologisch verträgliche Salzformen als pharmazeutische Wirkstoffe mit antiproliferativen und entzündungshemmenden Eigenschaften.
Long chain unbranched alkylamide derivs. of formula (I) and their physiologically acceptable salts which can be used as pharmaceuticals with antiproliferative and anti-inflammatory properties are new. Me(CH2)nNHR (I) n = 11-20; R = amino acid gps., their D- and L-enantiomers, di- and tri-peptides, N-protected forms and terminal ethyl esters.</description><edition>6</edition><language>eng ; fre ; ger</language><subject>CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>1995</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19950906&DB=EPODOC&CC=EP&NR=0670330A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25563,76318</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19950906&DB=EPODOC&CC=EP&NR=0670330A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>BERND, MICHAEL</creatorcontrib><creatorcontrib>GROSSMANN, HEINZ</creatorcontrib><creatorcontrib>ARP, JUERGEN</creatorcontrib><creatorcontrib>VOEGELI, R</creatorcontrib><creatorcontrib>LIEFLAENDER, MANFRED, DR</creatorcontrib><creatorcontrib>KUTSCHER, BERNHARD</creatorcontrib><creatorcontrib>ENGEL, JUERGEN</creatorcontrib><creatorcontrib>KICK, MARIA</creatorcontrib><title>Long-chain alkylamides of aminoacids and peptides with antiproliferative and antiinflammatory properties</title><description>Langkettige unverzweigte Alkylamide der allgemeinen Formel CH3-(CH2)n-NH-R, wobei n = 11 - 20 und R = Aminosäure, deren D- und L-Enantiomeren, Di- und Tripeptide, durch N-Schutzgruppen derivatisierte Formen und endständige Ethylester, sowie deren physiologisch verträgliche Salzformen als pharmazeutische Wirkstoffe mit antiproliferativen und entzündungshemmenden Eigenschaften.
Long chain unbranched alkylamide derivs. of formula (I) and their physiologically acceptable salts which can be used as pharmaceuticals with antiproliferative and anti-inflammatory properties are new. Me(CH2)nNHR (I) n = 11-20; R = amino acid gps., their D- and L-enantiomers, di- and tri-peptides, N-protected forms and terminal ethyl esters.</description><subject>CHEMISTRY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1995</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjEEKwjAQRbtxIeod5gKFSEDXIi0uXLhwX4ZkYgfTJCSD0tsbiwdw9T_vP_66Ga8xPFozIgdA_5w9TmypQHRQW4ho2BbAYCFRkmV6s4yVCKccPTvKKPyixflSDq6eTCgxz1CVRFmYyrZZOfSFdr_cNNB39_OlpRQHKgkNBZKhu6nDUWmtTnv9h_IB_bNBDg</recordid><startdate>19950906</startdate><enddate>19950906</enddate><creator>BERND, MICHAEL</creator><creator>GROSSMANN, HEINZ</creator><creator>ARP, JUERGEN</creator><creator>VOEGELI, R</creator><creator>LIEFLAENDER, MANFRED, DR</creator><creator>KUTSCHER, BERNHARD</creator><creator>ENGEL, JUERGEN</creator><creator>KICK, MARIA</creator><scope>EVB</scope></search><sort><creationdate>19950906</creationdate><title>Long-chain alkylamides of aminoacids and peptides with antiproliferative and antiinflammatory properties</title><author>BERND, MICHAEL ; GROSSMANN, HEINZ ; ARP, JUERGEN ; VOEGELI, R ; LIEFLAENDER, MANFRED, DR ; KUTSCHER, BERNHARD ; ENGEL, JUERGEN ; KICK, MARIA</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_EP0670330A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre ; ger</language><creationdate>1995</creationdate><topic>CHEMISTRY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>BERND, MICHAEL</creatorcontrib><creatorcontrib>GROSSMANN, HEINZ</creatorcontrib><creatorcontrib>ARP, JUERGEN</creatorcontrib><creatorcontrib>VOEGELI, R</creatorcontrib><creatorcontrib>LIEFLAENDER, MANFRED, DR</creatorcontrib><creatorcontrib>KUTSCHER, BERNHARD</creatorcontrib><creatorcontrib>ENGEL, JUERGEN</creatorcontrib><creatorcontrib>KICK, MARIA</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>BERND, MICHAEL</au><au>GROSSMANN, HEINZ</au><au>ARP, JUERGEN</au><au>VOEGELI, R</au><au>LIEFLAENDER, MANFRED, DR</au><au>KUTSCHER, BERNHARD</au><au>ENGEL, JUERGEN</au><au>KICK, MARIA</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Long-chain alkylamides of aminoacids and peptides with antiproliferative and antiinflammatory properties</title><date>1995-09-06</date><risdate>1995</risdate><abstract>Langkettige unverzweigte Alkylamide der allgemeinen Formel CH3-(CH2)n-NH-R, wobei n = 11 - 20 und R = Aminosäure, deren D- und L-Enantiomeren, Di- und Tripeptide, durch N-Schutzgruppen derivatisierte Formen und endständige Ethylester, sowie deren physiologisch verträgliche Salzformen als pharmazeutische Wirkstoffe mit antiproliferativen und entzündungshemmenden Eigenschaften.
Long chain unbranched alkylamide derivs. of formula (I) and their physiologically acceptable salts which can be used as pharmaceuticals with antiproliferative and anti-inflammatory properties are new. Me(CH2)nNHR (I) n = 11-20; R = amino acid gps., their D- and L-enantiomers, di- and tri-peptides, N-protected forms and terminal ethyl esters.</abstract><edition>6</edition><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng ; fre ; ger |
| recordid | cdi_epo_espacenet_EP0670330A1 |
| source | esp@cenet |
| subjects | CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | Long-chain alkylamides of aminoacids and peptides with antiproliferative and antiinflammatory properties |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-10T11%3A15%3A45IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=BERND,%20MICHAEL&rft.date=1995-09-06&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EEP0670330A1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |