Analogs of 15-deoxyspergualine, process for their preparation and their use as immunosuppressive agents

15-deoxy-spergualin analogues of formula (I) and their addn. salts are new. X = (CH2)n; Y = (CH2)4; T = (CH2)2; A = a single bond, -CH2-, -CH2O-, -CH2NH-, -CH(OH)-, -CHF-, or -CH(OCH3)-; n = 6-8. Intermediate cpds. of formula (II) are also claimed. A has the values above or in addn. is CH(OCH2C6H5);...

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Hauptverfasser: DUTARTRE, PATRICK, SAMRETH, SOTH, LEBRETON, LUC, RENAUT, PATRICE, DERREPAS, PHILIPPE
Format: Patent
Sprache:eng ; fre ; ger
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