Isopropyl-(2-methoxyethyl)-4-(2-chloro-3-cyano-phenyl)1,4-dihydro-2,6-dimethyl-piridine-3,5-dicarboxylate
Die vorliegende Erfindung betrifft die neue Verbindung rac-Isopropyl-(2-methoxyethyl)-4-(2-chlor-3-cyano-phenyl)-1,4-dihydro-2,6-dimethylpyridin-3,5-dicarboxylat und dessen reine Enantiomere, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel, insbesondere zur Behandlung von cerebra...
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| creator | GAO, ZHAN DR SCHOHE-LOOP, RUDOLF DR MEIER, HEINRICH DR DE JONG, MAARTEN DR SCHUURMAN, TEUNIS DR HARTWIG, WOLFGANG DR JUNGE, BODO DR SCHMIDT, BERNARD DR |
| description | Die vorliegende Erfindung betrifft die neue Verbindung rac-Isopropyl-(2-methoxyethyl)-4-(2-chlor-3-cyano-phenyl)-1,4-dihydro-2,6-dimethylpyridin-3,5-dicarboxylat und dessen reine Enantiomere, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel, insbesondere zur Behandlung von cerebralen und neuronalen Erkrankungen sowie ein neues Zwischenprodukt zur ihrer Herstellung.
The present invention relates to the compound rac-isopropyl 2-methoxyethyl 4-(2-chloro-3-cyanophenyl)-1,4-dihydro-2,6-dimethylpyridine-3,5-dicarb oxylate and its pure enantiomers, to processes for the preparation thereof and to the use thereof as pharmaceutical, in particular for treatment of cerebral and neuronal disorders and to an intermediate for the preparation thereof. |
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The present invention relates to the compound rac-isopropyl 2-methoxyethyl 4-(2-chloro-3-cyanophenyl)-1,4-dihydro-2,6-dimethylpyridine-3,5-dicarb oxylate and its pure enantiomers, to processes for the preparation thereof and to the use thereof as pharmaceutical, in particular for treatment of cerebral and neuronal disorders and to an intermediate for the preparation thereof.</description><edition>6</edition><language>eng ; fre ; ger</language><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS ; CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>1995</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19950614&DB=EPODOC&CC=EP&NR=0657430A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19950614&DB=EPODOC&CC=EP&NR=0657430A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>GAO, ZHAN DR</creatorcontrib><creatorcontrib>SCHOHE-LOOP, RUDOLF DR</creatorcontrib><creatorcontrib>MEIER, HEINRICH DR</creatorcontrib><creatorcontrib>DE JONG, MAARTEN DR</creatorcontrib><creatorcontrib>SCHUURMAN, TEUNIS DR</creatorcontrib><creatorcontrib>HARTWIG, WOLFGANG DR</creatorcontrib><creatorcontrib>JUNGE, BODO DR</creatorcontrib><creatorcontrib>SCHMIDT, BERNARD DR</creatorcontrib><title>Isopropyl-(2-methoxyethyl)-4-(2-chloro-3-cyano-phenyl)1,4-dihydro-2,6-dimethyl-piridine-3,5-dicarboxylate</title><description>Die vorliegende Erfindung betrifft die neue Verbindung rac-Isopropyl-(2-methoxyethyl)-4-(2-chlor-3-cyano-phenyl)-1,4-dihydro-2,6-dimethylpyridin-3,5-dicarboxylat und dessen reine Enantiomere, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel, insbesondere zur Behandlung von cerebralen und neuronalen Erkrankungen sowie ein neues Zwischenprodukt zur ihrer Herstellung.
The present invention relates to the compound rac-isopropyl 2-methoxyethyl 4-(2-chloro-3-cyanophenyl)-1,4-dihydro-2,6-dimethylpyridine-3,5-dicarb oxylate and its pure enantiomers, to processes for the preparation thereof and to the use thereof as pharmaceutical, in particular for treatment of cerebral and neuronal disorders and to an intermediate for the preparation thereof.</description><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS</subject><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1995</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNTLsKwjAUzeIg6j84KuRC27R1Fqno5uBeYnolgTQ3JBnM3xvFD3A553BeS2aukXwgny3sGpgxaXrlgtnuof1YSlsKBAJUlo7Aa3Qlq3kLk9F5KlHD-6Ln7wi8CWYyDkHwrrhKhkc5tDLhmi2e0kbc_HjFtufhfroAehoxeqnQYRqHW9V3h1ZUx1r8UXkDZy89zg</recordid><startdate>19950614</startdate><enddate>19950614</enddate><creator>GAO, ZHAN DR</creator><creator>SCHOHE-LOOP, RUDOLF DR</creator><creator>MEIER, HEINRICH DR</creator><creator>DE JONG, MAARTEN DR</creator><creator>SCHUURMAN, TEUNIS DR</creator><creator>HARTWIG, WOLFGANG DR</creator><creator>JUNGE, BODO DR</creator><creator>SCHMIDT, BERNARD DR</creator><scope>EVB</scope></search><sort><creationdate>19950614</creationdate><title>Isopropyl-(2-methoxyethyl)-4-(2-chloro-3-cyano-phenyl)1,4-dihydro-2,6-dimethyl-piridine-3,5-dicarboxylate</title><author>GAO, ZHAN DR ; SCHOHE-LOOP, RUDOLF DR ; MEIER, HEINRICH DR ; DE JONG, MAARTEN DR ; SCHUURMAN, TEUNIS DR ; HARTWIG, WOLFGANG DR ; JUNGE, BODO DR ; SCHMIDT, BERNARD DR</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_EP0657430A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre ; ger</language><creationdate>1995</creationdate><topic>ACYCLIC OR CARBOCYCLIC COMPOUNDS</topic><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>GAO, ZHAN DR</creatorcontrib><creatorcontrib>SCHOHE-LOOP, RUDOLF DR</creatorcontrib><creatorcontrib>MEIER, HEINRICH DR</creatorcontrib><creatorcontrib>DE JONG, MAARTEN DR</creatorcontrib><creatorcontrib>SCHUURMAN, TEUNIS DR</creatorcontrib><creatorcontrib>HARTWIG, WOLFGANG DR</creatorcontrib><creatorcontrib>JUNGE, BODO DR</creatorcontrib><creatorcontrib>SCHMIDT, BERNARD DR</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>GAO, ZHAN DR</au><au>SCHOHE-LOOP, RUDOLF DR</au><au>MEIER, HEINRICH DR</au><au>DE JONG, MAARTEN DR</au><au>SCHUURMAN, TEUNIS DR</au><au>HARTWIG, WOLFGANG DR</au><au>JUNGE, BODO DR</au><au>SCHMIDT, BERNARD DR</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Isopropyl-(2-methoxyethyl)-4-(2-chloro-3-cyano-phenyl)1,4-dihydro-2,6-dimethyl-piridine-3,5-dicarboxylate</title><date>1995-06-14</date><risdate>1995</risdate><abstract>Die vorliegende Erfindung betrifft die neue Verbindung rac-Isopropyl-(2-methoxyethyl)-4-(2-chlor-3-cyano-phenyl)-1,4-dihydro-2,6-dimethylpyridin-3,5-dicarboxylat und dessen reine Enantiomere, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel, insbesondere zur Behandlung von cerebralen und neuronalen Erkrankungen sowie ein neues Zwischenprodukt zur ihrer Herstellung.
The present invention relates to the compound rac-isopropyl 2-methoxyethyl 4-(2-chloro-3-cyanophenyl)-1,4-dihydro-2,6-dimethylpyridine-3,5-dicarb oxylate and its pure enantiomers, to processes for the preparation thereof and to the use thereof as pharmaceutical, in particular for treatment of cerebral and neuronal disorders and to an intermediate for the preparation thereof.</abstract><edition>6</edition><oa>free_for_read</oa></addata></record> |
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| subjects | ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | Isopropyl-(2-methoxyethyl)-4-(2-chloro-3-cyano-phenyl)1,4-dihydro-2,6-dimethyl-piridine-3,5-dicarboxylate |
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