Compositions of iodobenzoic acid derivatives in filmforming materials for visualization of the gastrointestinal tract
Disclosed are x-ray contrast compositions for oral or retrograde examination of the GI tract comprising a polymeric material capable of forming a coating on the GI tract, said polymeric material having atoms containing polarizable electrons thereon, in combination with a divalent cation; and an x-ra...
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creator | DOUTY BRENT D C O STERLING WIN ILLIG CARL R C O STERLING WINT |
description | Disclosed are x-ray contrast compositions for oral or retrograde examination of the GI tract comprising a polymeric material capable of forming a coating on the GI tract, said polymeric material having atoms containing polarizable electrons thereon, in combination with a divalent cation; and an x-ray contrast producing agent of the formulawhereinZ = H, halo, C1-C20 alkyl, cycloalkyl, lower alkoxy, cyano, where the alkyl and cycloalkyl groups can be substituted with halogen or halo-lower-alkyl groups;R = C1-C25 alkyl, cycloalkyl, or halo-lower-alkyl, optionally substituted with halo, fluoro-lower-alkyl, aryl, lower-alkoxy, hydroxy, carboxy, lower-alkoxy carbonyl or lower-alkoxy-carbonyloxy, (CR1R2)p - (CR3 = CR4)mQ, or (CR1 R2)p - C ≡ C - Q;Ri, R2, R3 and R4 are independently lower-alkyl, optionally substituted with halo;x is 1-3y is 1-4;n is 1-5;m is 1-15;p is 1-10; andQ is H, lower-alkyl, lower-alkenyl, lower-alkynyl, lower-alkylene, aryl, or aryl-lower alkyl; in a pharmaceutically acceptable carrier and a method of its use in diagnostic radiology of the GI tract. |
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and an x-ray contrast producing agent of the formulawhereinZ = H, halo, C1-C20 alkyl, cycloalkyl, lower alkoxy, cyano, where the alkyl and cycloalkyl groups can be substituted with halogen or halo-lower-alkyl groups;R = C1-C25 alkyl, cycloalkyl, or halo-lower-alkyl, optionally substituted with halo, fluoro-lower-alkyl, aryl, lower-alkoxy, hydroxy, carboxy, lower-alkoxy carbonyl or lower-alkoxy-carbonyloxy, (CR1R2)p - (CR3 = CR4)mQ, or (CR1 R2)p - C ≡ C - Q;Ri, R2, R3 and R4 are independently lower-alkyl, optionally substituted with halo;x is 1-3y is 1-4;n is 1-5;m is 1-15;p is 1-10; andQ is H, lower-alkyl, lower-alkenyl, lower-alkynyl, lower-alkylene, aryl, or aryl-lower alkyl; in a pharmaceutically acceptable carrier and a method of its use in diagnostic radiology of the GI tract.</description><edition>5</edition><language>eng ; fre ; ger</language><subject>CHEMISTRY ; COMPOSITIONS BASED THEREON ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC MACROMOLECULAR COMPOUNDS ; 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and an x-ray contrast producing agent of the formulawhereinZ = H, halo, C1-C20 alkyl, cycloalkyl, lower alkoxy, cyano, where the alkyl and cycloalkyl groups can be substituted with halogen or halo-lower-alkyl groups;R = C1-C25 alkyl, cycloalkyl, or halo-lower-alkyl, optionally substituted with halo, fluoro-lower-alkyl, aryl, lower-alkoxy, hydroxy, carboxy, lower-alkoxy carbonyl or lower-alkoxy-carbonyloxy, (CR1R2)p - (CR3 = CR4)mQ, or (CR1 R2)p - C ≡ C - Q;Ri, R2, R3 and R4 are independently lower-alkyl, optionally substituted with halo;x is 1-3y is 1-4;n is 1-5;m is 1-15;p is 1-10; andQ is H, lower-alkyl, lower-alkenyl, lower-alkynyl, lower-alkylene, aryl, or aryl-lower alkyl; in a pharmaceutically acceptable carrier and a method of its use in diagnostic radiology of the GI tract.</description><subject>CHEMISTRY</subject><subject>COMPOSITIONS BASED THEREON</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC MACROMOLECULAR COMPOUNDS</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>THEIR PREPARATION OR CHEMICAL WORKING-UP</subject><subject>USE OF INORGANIC OR NON-MACROMOLECULAR ORGANIC SUBSTANCES ASCOMPOUNDING INGREDIENTS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1995</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjDEKwkAQRdNYiHqHuYCgRAKWEiKWFvZh3MzGgd2dsDNJkdObgAew-vD_-29bjLXEQZSNJSmIB5ZO3pRmYQfouIOOMk9oPJECJ_AcopccOfUQ0ZYRg8LSwMQ6YuAZV9eqsg9Bj2pZOBmpccIAltHZvtj45UaHX-4KuDev-nGkQVrSAR0lsrZ5nqrzpaqut7L8A_kCHmRGWw</recordid><startdate>19950607</startdate><enddate>19950607</enddate><creator>DOUTY BRENT D C O STERLING WIN</creator><creator>ILLIG CARL R C O STERLING WINT</creator><scope>EVB</scope></search><sort><creationdate>19950607</creationdate><title>Compositions of iodobenzoic acid derivatives in filmforming materials for visualization of the gastrointestinal tract</title><author>DOUTY BRENT D C O STERLING WIN ; ILLIG CARL R C O STERLING WINT</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_EP0614669A33</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre ; ger</language><creationdate>1995</creationdate><topic>CHEMISTRY</topic><topic>COMPOSITIONS BASED THEREON</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC MACROMOLECULAR COMPOUNDS</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>THEIR PREPARATION OR CHEMICAL WORKING-UP</topic><topic>USE OF INORGANIC OR NON-MACROMOLECULAR ORGANIC SUBSTANCES ASCOMPOUNDING INGREDIENTS</topic><toplevel>online_resources</toplevel><creatorcontrib>DOUTY BRENT D C O STERLING WIN</creatorcontrib><creatorcontrib>ILLIG CARL R C O STERLING WINT</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>DOUTY BRENT D C O STERLING WIN</au><au>ILLIG CARL R C O STERLING WINT</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Compositions of iodobenzoic acid derivatives in filmforming materials for visualization of the gastrointestinal tract</title><date>1995-06-07</date><risdate>1995</risdate><abstract>Disclosed are x-ray contrast compositions for oral or retrograde examination of the GI tract comprising a polymeric material capable of forming a coating on the GI tract, said polymeric material having atoms containing polarizable electrons thereon, in combination with a divalent cation; and an x-ray contrast producing agent of the formulawhereinZ = H, halo, C1-C20 alkyl, cycloalkyl, lower alkoxy, cyano, where the alkyl and cycloalkyl groups can be substituted with halogen or halo-lower-alkyl groups;R = C1-C25 alkyl, cycloalkyl, or halo-lower-alkyl, optionally substituted with halo, fluoro-lower-alkyl, aryl, lower-alkoxy, hydroxy, carboxy, lower-alkoxy carbonyl or lower-alkoxy-carbonyloxy, (CR1R2)p - (CR3 = CR4)mQ, or (CR1 R2)p - C ≡ C - Q;Ri, R2, R3 and R4 are independently lower-alkyl, optionally substituted with halo;x is 1-3y is 1-4;n is 1-5;m is 1-15;p is 1-10; andQ is H, lower-alkyl, lower-alkenyl, lower-alkynyl, lower-alkylene, aryl, or aryl-lower alkyl; in a pharmaceutically acceptable carrier and a method of its use in diagnostic radiology of the GI tract.</abstract><edition>5</edition><oa>free_for_read</oa></addata></record> |
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language | eng ; fre ; ger |
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subjects | CHEMISTRY COMPOSITIONS BASED THEREON HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC MACROMOLECULAR COMPOUNDS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES THEIR PREPARATION OR CHEMICAL WORKING-UP USE OF INORGANIC OR NON-MACROMOLECULAR ORGANIC SUBSTANCES ASCOMPOUNDING INGREDIENTS |
title | Compositions of iodobenzoic acid derivatives in filmforming materials for visualization of the gastrointestinal tract |
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