Cephalosporin compounds and processes for the preparation thereof

The present invention relates to a cephalosporin compound including the pharmaceutically acceptable non-toxic salts, physiologically hydrolyzable esters, hydrates and solvates thereof of the formula(I) and its isomers: wherein: R is a C1-4 alkyl, C3-4 alkenyl, C3-4 alkynyl or -C(R)(R)-COOH wherein R...

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Hauptverfasser: NAHM, KEE PYUNG, KIM, YONG ZU, SEO, MI KYEONG, BANG, CHAN SIK, YEO, JAE HONG, LIM, JONG CHAN, OH, HUN SEUNG
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creator NAHM, KEE PYUNG
KIM, YONG ZU
SEO, MI KYEONG
BANG, CHAN SIK
YEO, JAE HONG
LIM, JONG CHAN
OH, HUN SEUNG
description The present invention relates to a cephalosporin compound including the pharmaceutically acceptable non-toxic salts, physiologically hydrolyzable esters, hydrates and solvates thereof of the formula(I) and its isomers: wherein: R is a C1-4 alkyl, C3-4 alkenyl, C3-4 alkynyl or -C(R)(R)-COOH wherein R and R are, independently of each other, a hydrogen or a C1-4 alkyl group, respectively, or jointly form a C3-7 cycloalkyl group together with the carbon atoms to which they are attached; R is a hydrogen or an amino which may be substituted or unsubstituted, alkoxy or heterocyclic group which is linked with a nitrogen atom; R is a hydrogen or a C1-4 alkyl, amino, aminomethyl, hydroxy, hydroxymethyl, carboxy or carboxymethyl group; R is a hydrogen or a C1-4 alkyl, amino, hydroxy, hydroxyalkl, acetamide, carboxyalkyl or sulfonylethyl group; R is a hydrogen or a C1-4 alkyl, amino, carboxy, carboxyalkyl or hydroxy group; and Q and T are independently CH or N, provided that R is an amino group when T is N.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Cephalosporin compounds and processes for the preparation thereof
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