Fluid analysis
The invention provides a method and apparatus for the preliminary detection of abnormal levels of metabolites in the urine of a human or animal. The method includes the steps of determining the amount of creatinine in the urine of the human or animal, measuring the total metabolites content in the u...
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| creator | UECKERMANN, JULIUS HEINRICH ELS, HENNING JOHANNES VAN STEENDEREN, RONALD ADRIAAN ERASMUS, ELARDUS MIENIE, LODEWYK JACOBUS DE WET, WOUTER JOHANNES |
| description | The invention provides a method and apparatus for the preliminary detection of abnormal levels of metabolites in the urine of a human or animal. The method includes the steps of determining the amount of creatinine in the urine of the human or animal, measuring the total metabolites content in the urine, using the amount of creatinine in the urine as an internal standard to compensate for variations in the urine concentration, and comparing the total metabolites content in the urine with a reference value which corresponds to the expected total metabolites content in the urine of a person or animal who does not suffer from a metabolic disorder. The apparatus (10) includes an ultraviolet oxidation unit (16) for oxidising total metabolites in a urine sample to carbon dioxide, an organic carbon stripper (18) for stripping carbon dioxide gas from the oxidised sample, and a carbon dioxide detector (69) for measuring the amount of carbon dioxide produced from the sample. |
| format | Patent |
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The method includes the steps of determining the amount of creatinine in the urine of the human or animal, measuring the total metabolites content in the urine, using the amount of creatinine in the urine as an internal standard to compensate for variations in the urine concentration, and comparing the total metabolites content in the urine with a reference value which corresponds to the expected total metabolites content in the urine of a person or animal who does not suffer from a metabolic disorder. The apparatus (10) includes an ultraviolet oxidation unit (16) for oxidising total metabolites in a urine sample to carbon dioxide, an organic carbon stripper (18) for stripping carbon dioxide gas from the oxidised sample, and a carbon dioxide detector (69) for measuring the amount of carbon dioxide produced from the sample.</description><edition>5</edition><language>eng ; fre ; ger</language><subject>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES ; MEASURING ; PHYSICS ; TESTING</subject><creationdate>1994</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19940126&DB=EPODOC&CC=EP&NR=0580383A2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19940126&DB=EPODOC&CC=EP&NR=0580383A2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>UECKERMANN, JULIUS HEINRICH</creatorcontrib><creatorcontrib>ELS, HENNING JOHANNES</creatorcontrib><creatorcontrib>VAN STEENDEREN, RONALD ADRIAAN</creatorcontrib><creatorcontrib>ERASMUS, ELARDUS</creatorcontrib><creatorcontrib>MIENIE, LODEWYK JACOBUS</creatorcontrib><creatorcontrib>DE WET, WOUTER JOHANNES</creatorcontrib><title>Fluid analysis</title><description>The invention provides a method and apparatus for the preliminary detection of abnormal levels of metabolites in the urine of a human or animal. 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The method includes the steps of determining the amount of creatinine in the urine of the human or animal, measuring the total metabolites content in the urine, using the amount of creatinine in the urine as an internal standard to compensate for variations in the urine concentration, and comparing the total metabolites content in the urine with a reference value which corresponds to the expected total metabolites content in the urine of a person or animal who does not suffer from a metabolic disorder. The apparatus (10) includes an ultraviolet oxidation unit (16) for oxidising total metabolites in a urine sample to carbon dioxide, an organic carbon stripper (18) for stripping carbon dioxide gas from the oxidised sample, and a carbon dioxide detector (69) for measuring the amount of carbon dioxide produced from the sample.</abstract><edition>5</edition><oa>free_for_read</oa></addata></record> |
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| subjects | INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING PHYSICS TESTING |
| title | Fluid analysis |
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