INSULIN ANALOGS

Analogs of human insulin containing an Asp residue at position 10 of the B chain, having a truncated carboxyl terminus of the B chain and, optionally, having modifications at other positions display modified physico-chemical and pharmacokinetic properties. These analogs are useful in the treatment o...

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Bibliographische Detailangaben
Hauptverfasser:	CHANCE, RONALD EUGENE, BREMS, DAVID NETTLESHIP, FRANK, BRUCE HILL
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	Analogs of human insulin containing an Asp residue at position 10 of the B chain, having a truncated carboxyl terminus of the B chain and, optionally, having modifications at other positions display modified physico-chemical and pharmacokinetic properties. These analogs are useful in the treatment of hyperglycemia.