Process for obtaining polymers with antiviral activity
The present invention consists in a process for obtaining polymers with antiviral activity which is characterized in that beginning with oligo or polysaccharides with a specific structure, polymers with a specific number of carbonyl groups are obtained by oxidation; in that the carbonyl groups of th...
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creator | PIVEL RANIERI, JUAN PABLO LEAL OJEDA, JUAN ANTONIO GUERRERO, GOMEZ-PAMO, ANTONIO F CARRASCO, LLAMAS, LUIS GUERRERO BENITO, CARMEN ALMELA ARMENDARIZ, MARIA JESUS |
description | The present invention consists in a process for obtaining polymers with antiviral activity which is characterized in that beginning with oligo or polysaccharides with a specific structure, polymers with a specific number of carbonyl groups are obtained by oxidation; in that the carbonyl groups of the oxidised oligo/polysaccharides are made to react with amino groups of molecules carrying amino and sulfonated groups, such as aliphatic amino-sulfonates, in water or in mictures of water with water-miscible solvents, under specific temperature, time, and pH conditions, giving rise to polymers carrying sulfonated groups, which are purified by conventional processes; in that the sulfonated polymers thus obtained have antiviral activity and either lack or present very low toxicity and anticoagulant activity, and are thus suitable for the production of pharmaceutical preparations suitable for use in topical or systemic antiviral therapy in humans or in animals. It is applicable in the pharmaceutical industry. |
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It is applicable in the pharmaceutical industry.</description><subject>CHEMISTRY</subject><subject>COMPOSITIONS BASED THEREON</subject><subject>DERIVATIVES THEREOF</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC MACROMOLECULAR COMPOUNDS</subject><subject>POLYSACCHARIDES</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><subject>THEIR PREPARATION OR CHEMICAL WORKING-UP</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1992</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZDALKMpPTi0uVkjLL1LITypJzMzLzEtXKMjPqcxNLSpWKM8syVBIzCvJLMssSsxRSEwGsUoqeRhY0xJzilN5oTQ3g4Kba4izh25qQX58anFBYnJqXmpJvGuAgYmloZmJiaORMRFKAIhSLc4</recordid><startdate>19920624</startdate><enddate>19920624</enddate><creator>PIVEL RANIERI, JUAN PABLO</creator><creator>LEAL OJEDA, JUAN ANTONIO</creator><creator>GUERRERO, GOMEZ-PAMO, ANTONIO F</creator><creator>CARRASCO, LLAMAS, LUIS</creator><creator>GUERRERO BENITO, CARMEN</creator><creator>ALMELA ARMENDARIZ, MARIA JESUS</creator><scope>EVB</scope></search><sort><creationdate>19920624</creationdate><title>Process for obtaining polymers with antiviral activity</title><author>PIVEL RANIERI, JUAN PABLO ; LEAL OJEDA, JUAN ANTONIO ; GUERRERO, GOMEZ-PAMO, ANTONIO F ; CARRASCO, LLAMAS, LUIS ; GUERRERO BENITO, CARMEN ; ALMELA ARMENDARIZ, MARIA JESUS</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_EP0491644A23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre ; ger</language><creationdate>1992</creationdate><topic>CHEMISTRY</topic><topic>COMPOSITIONS BASED THEREON</topic><topic>DERIVATIVES THEREOF</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC MACROMOLECULAR COMPOUNDS</topic><topic>POLYSACCHARIDES</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><topic>THEIR PREPARATION OR CHEMICAL WORKING-UP</topic><toplevel>online_resources</toplevel><creatorcontrib>PIVEL RANIERI, JUAN PABLO</creatorcontrib><creatorcontrib>LEAL OJEDA, JUAN ANTONIO</creatorcontrib><creatorcontrib>GUERRERO, GOMEZ-PAMO, ANTONIO F</creatorcontrib><creatorcontrib>CARRASCO, LLAMAS, LUIS</creatorcontrib><creatorcontrib>GUERRERO BENITO, CARMEN</creatorcontrib><creatorcontrib>ALMELA ARMENDARIZ, MARIA JESUS</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>PIVEL RANIERI, JUAN PABLO</au><au>LEAL OJEDA, JUAN ANTONIO</au><au>GUERRERO, GOMEZ-PAMO, ANTONIO F</au><au>CARRASCO, LLAMAS, LUIS</au><au>GUERRERO BENITO, CARMEN</au><au>ALMELA ARMENDARIZ, MARIA JESUS</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Process for obtaining polymers with antiviral activity</title><date>1992-06-24</date><risdate>1992</risdate><abstract>The present invention consists in a process for obtaining polymers with antiviral activity which is characterized in that beginning with oligo or polysaccharides with a specific structure, polymers with a specific number of carbonyl groups are obtained by oxidation; in that the carbonyl groups of the oxidised oligo/polysaccharides are made to react with amino groups of molecules carrying amino and sulfonated groups, such as aliphatic amino-sulfonates, in water or in mictures of water with water-miscible solvents, under specific temperature, time, and pH conditions, giving rise to polymers carrying sulfonated groups, which are purified by conventional processes; in that the sulfonated polymers thus obtained have antiviral activity and either lack or present very low toxicity and anticoagulant activity, and are thus suitable for the production of pharmaceutical preparations suitable for use in topical or systemic antiviral therapy in humans or in animals. It is applicable in the pharmaceutical industry.</abstract><oa>free_for_read</oa></addata></record> |
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subjects | CHEMISTRY COMPOSITIONS BASED THEREON DERIVATIVES THEREOF HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC MACROMOLECULAR COMPOUNDS POLYSACCHARIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS THEIR PREPARATION OR CHEMICAL WORKING-UP |
title | Process for obtaining polymers with antiviral activity |
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