Process for obtaining polymers with antiviral activity
The present invention consists in a process for obtaining polymers with antiviral activity which is characterised in that in water or in mixtures of water with water-miscible solvents, ruder specific conditions of temperature, time, and pH, molecules carrying carbonyl groups and hydroxyl groups in a...
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| creator | PIVEL RANIERI, JUAN PABLO CARRASCO LLAMAS, LUIS GUERRERO BENITO, CARMEN, URB. EL PARQUE - BLOQ. 12 GUERRERO GOMEZ-PAMO, ANTONIO F LEAL OJEDA, JUAN ANTONIO ALMELA ARMENDARIZ, MARIA JESUS |
| description | The present invention consists in a process for obtaining polymers with antiviral activity which is characterised in that in water or in mixtures of water with water-miscible solvents, ruder specific conditions of temperature, time, and pH, molecules carrying carbonyl groups and hydroxyl groups in alpha position relative to the carbonyl, such as monosaccharides, react with molecules carrying amino and sulfonated groups, such as aliphatic amino-sulfonates; in that after the reaction ends, the polymeric material is purified by conventional processes, such that its molecular weight is within the range from 1,500 to 100,000; in that this polymeric material has antiviral activity and either lacks or presents very low toxicity and anticoagulant activity, and is thus suitable for production of pharmaceutical preparations suitable for use in topical or systemic antiviral therapy in humans or in animals. It is applicable in the pharmaceutical industry. |
| format | Patent |
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EL PARQUE - BLOQ. 12 ; GUERRERO GOMEZ-PAMO, ANTONIO F ; LEAL OJEDA, JUAN ANTONIO ; ALMELA ARMENDARIZ, MARIA JESUS</creator><creatorcontrib>PIVEL RANIERI, JUAN PABLO ; CARRASCO LLAMAS, LUIS ; GUERRERO BENITO, CARMEN, URB. EL PARQUE - BLOQ. 12 ; GUERRERO GOMEZ-PAMO, ANTONIO F ; LEAL OJEDA, JUAN ANTONIO ; ALMELA ARMENDARIZ, MARIA JESUS</creatorcontrib><description>The present invention consists in a process for obtaining polymers with antiviral activity which is characterised in that in water or in mixtures of water with water-miscible solvents, ruder specific conditions of temperature, time, and pH, molecules carrying carbonyl groups and hydroxyl groups in alpha position relative to the carbonyl, such as monosaccharides, react with molecules carrying amino and sulfonated groups, such as aliphatic amino-sulfonates; in that after the reaction ends, the polymeric material is purified by conventional processes, such that its molecular weight is within the range from 1,500 to 100,000; in that this polymeric material has antiviral activity and either lacks or presents very low toxicity and anticoagulant activity, and is thus suitable for production of pharmaceutical preparations suitable for use in topical or systemic antiviral therapy in humans or in animals. It is applicable in the pharmaceutical industry.</description><edition>6</edition><language>eng ; fre ; ger</language><subject>CHEMISTRY ; COMPOSITIONS BASED THEREON ; DERIVATIVES THEREOF ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC MACROMOLECULAR COMPOUNDS ; POLYSACCHARIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS ; THEIR PREPARATION OR CHEMICAL WORKING-UP</subject><creationdate>1996</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19960814&DB=EPODOC&CC=EP&NR=0491643B1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19960814&DB=EPODOC&CC=EP&NR=0491643B1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>PIVEL RANIERI, JUAN PABLO</creatorcontrib><creatorcontrib>CARRASCO LLAMAS, LUIS</creatorcontrib><creatorcontrib>GUERRERO BENITO, CARMEN, URB. 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EL PARQUE - BLOQ. 12</creatorcontrib><creatorcontrib>GUERRERO GOMEZ-PAMO, ANTONIO F</creatorcontrib><creatorcontrib>LEAL OJEDA, JUAN ANTONIO</creatorcontrib><creatorcontrib>ALMELA ARMENDARIZ, MARIA JESUS</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>PIVEL RANIERI, JUAN PABLO</au><au>CARRASCO LLAMAS, LUIS</au><au>GUERRERO BENITO, CARMEN, URB. EL PARQUE - BLOQ. 12</au><au>GUERRERO GOMEZ-PAMO, ANTONIO F</au><au>LEAL OJEDA, JUAN ANTONIO</au><au>ALMELA ARMENDARIZ, MARIA JESUS</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Process for obtaining polymers with antiviral activity</title><date>1996-08-14</date><risdate>1996</risdate><abstract>The present invention consists in a process for obtaining polymers with antiviral activity which is characterised in that in water or in mixtures of water with water-miscible solvents, ruder specific conditions of temperature, time, and pH, molecules carrying carbonyl groups and hydroxyl groups in alpha position relative to the carbonyl, such as monosaccharides, react with molecules carrying amino and sulfonated groups, such as aliphatic amino-sulfonates; in that after the reaction ends, the polymeric material is purified by conventional processes, such that its molecular weight is within the range from 1,500 to 100,000; in that this polymeric material has antiviral activity and either lacks or presents very low toxicity and anticoagulant activity, and is thus suitable for production of pharmaceutical preparations suitable for use in topical or systemic antiviral therapy in humans or in animals. It is applicable in the pharmaceutical industry.</abstract><edition>6</edition><oa>free_for_read</oa></addata></record> |
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| language | eng ; fre ; ger |
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| subjects | CHEMISTRY COMPOSITIONS BASED THEREON DERIVATIVES THEREOF HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC MACROMOLECULAR COMPOUNDS POLYSACCHARIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS THEIR PREPARATION OR CHEMICAL WORKING-UP |
| title | Process for obtaining polymers with antiviral activity |
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