HIGH LEVEL EXPRESSION OF FUNCTIONAL HUMAN PLASMINOGEN ACTIVATOR INHIBITOR (PAI-1) IN -i(E. COLI)
L'invention concerne PAI-1 de recombinaison mature et biologiquement fonctionnel exprimée par E. coli, ainsi que des vecteurs d'expression de plasmide pour la production de rPAI-1, ainsi qu'un procédé d'identification d'inhibiteurs de la liaison de PAI-1 et t-PA. Biologicall...
Gespeichert in:
| Hauptverfasser: | , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng ; fre ; ger |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | DAVIS, GARY, LEE KNABB, ROBERT, MADARA SISK, WILLIAM, PERRY REILLY, THOMAS, MICHAEL |
| description | L'invention concerne PAI-1 de recombinaison mature et biologiquement fonctionnel exprimée par E. coli, ainsi que des vecteurs d'expression de plasmide pour la production de rPAI-1, ainsi qu'un procédé d'identification d'inhibiteurs de la liaison de PAI-1 et t-PA.
Biologically functional mature E. coli-expressed recombinant PAI-1 is disclosed, as well as plasmid expression vectors for production of rPAI-1, and a method for identifying inhibitors of the binding of PAI-1 and t-PA. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_EP0471759A1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>EP0471759A1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_EP0471759A13</originalsourceid><addsrcrecordid>eNqNisEKgkAURd20iOof3lIXE0mJtHzJ03kwzgzOKO1MYoIgSrD_J4M-oNU5nHuX0UVyJUFRRwrobBtyjo0GU0LZ6sLPjgpkW6MGq9DVrE1FGnCeOvSmAdaST_y12CKLNJkLiHtMWyiM4mQdLW7DYwqbH1cRlOQLKcL46sM0DtfwDO-e7O6Qp3l2xHT_x-UD2kEyTQ</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>HIGH LEVEL EXPRESSION OF FUNCTIONAL HUMAN PLASMINOGEN ACTIVATOR INHIBITOR (PAI-1) IN -i(E. COLI)</title><source>esp@cenet</source><creator>DAVIS, GARY, LEE ; KNABB, ROBERT, MADARA ; SISK, WILLIAM, PERRY ; REILLY, THOMAS, MICHAEL</creator><creatorcontrib>DAVIS, GARY, LEE ; KNABB, ROBERT, MADARA ; SISK, WILLIAM, PERRY ; REILLY, THOMAS, MICHAEL</creatorcontrib><description>L'invention concerne PAI-1 de recombinaison mature et biologiquement fonctionnel exprimée par E. coli, ainsi que des vecteurs d'expression de plasmide pour la production de rPAI-1, ainsi qu'un procédé d'identification d'inhibiteurs de la liaison de PAI-1 et t-PA.
Biologically functional mature E. coli-expressed recombinant PAI-1 is disclosed, as well as plasmid expression vectors for production of rPAI-1, and a method for identifying inhibitors of the binding of PAI-1 and t-PA.</description><language>eng ; fre ; ger</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; ENZYMOLOGY ; FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE ; HUMAN NECESSITIES ; HYGIENE ; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES ; MEASURING ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; ORGANIC CHEMISTRY ; PEPTIDES ; PHYSICS ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; PROCESSES USING MICROORGANISMS ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS ; SPIRITS ; TESTING ; VINEGAR ; WINE</subject><creationdate>1992</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19920226&DB=EPODOC&CC=EP&NR=0471759A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19920226&DB=EPODOC&CC=EP&NR=0471759A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>DAVIS, GARY, LEE</creatorcontrib><creatorcontrib>KNABB, ROBERT, MADARA</creatorcontrib><creatorcontrib>SISK, WILLIAM, PERRY</creatorcontrib><creatorcontrib>REILLY, THOMAS, MICHAEL</creatorcontrib><title>HIGH LEVEL EXPRESSION OF FUNCTIONAL HUMAN PLASMINOGEN ACTIVATOR INHIBITOR (PAI-1) IN -i(E. COLI)</title><description>L'invention concerne PAI-1 de recombinaison mature et biologiquement fonctionnel exprimée par E. coli, ainsi que des vecteurs d'expression de plasmide pour la production de rPAI-1, ainsi qu'un procédé d'identification d'inhibiteurs de la liaison de PAI-1 et t-PA.
Biologically functional mature E. coli-expressed recombinant PAI-1 is disclosed, as well as plasmid expression vectors for production of rPAI-1, and a method for identifying inhibitors of the binding of PAI-1 and t-PA.</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS THEREOF</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</subject><subject>MEASURING</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PHYSICS</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>PROCESSES USING MICROORGANISMS</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><subject>SPIRITS</subject><subject>TESTING</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1992</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNisEKgkAURd20iOof3lIXE0mJtHzJ03kwzgzOKO1MYoIgSrD_J4M-oNU5nHuX0UVyJUFRRwrobBtyjo0GU0LZ6sLPjgpkW6MGq9DVrE1FGnCeOvSmAdaST_y12CKLNJkLiHtMWyiM4mQdLW7DYwqbH1cRlOQLKcL46sM0DtfwDO-e7O6Qp3l2xHT_x-UD2kEyTQ</recordid><startdate>19920226</startdate><enddate>19920226</enddate><creator>DAVIS, GARY, LEE</creator><creator>KNABB, ROBERT, MADARA</creator><creator>SISK, WILLIAM, PERRY</creator><creator>REILLY, THOMAS, MICHAEL</creator><scope>EVB</scope></search><sort><creationdate>19920226</creationdate><title>HIGH LEVEL EXPRESSION OF FUNCTIONAL HUMAN PLASMINOGEN ACTIVATOR INHIBITOR (PAI-1) IN -i(E. COLI)</title><author>DAVIS, GARY, LEE ; KNABB, ROBERT, MADARA ; SISK, WILLIAM, PERRY ; REILLY, THOMAS, MICHAEL</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_EP0471759A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre ; ger</language><creationdate>1992</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS THEREOF</topic><topic>CULTURE MEDIA</topic><topic>ENZYMOLOGY</topic><topic>FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</topic><topic>MEASURING</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PHYSICS</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>PROCESSES USING MICROORGANISMS</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><topic>SPIRITS</topic><topic>TESTING</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>DAVIS, GARY, LEE</creatorcontrib><creatorcontrib>KNABB, ROBERT, MADARA</creatorcontrib><creatorcontrib>SISK, WILLIAM, PERRY</creatorcontrib><creatorcontrib>REILLY, THOMAS, MICHAEL</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>DAVIS, GARY, LEE</au><au>KNABB, ROBERT, MADARA</au><au>SISK, WILLIAM, PERRY</au><au>REILLY, THOMAS, MICHAEL</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>HIGH LEVEL EXPRESSION OF FUNCTIONAL HUMAN PLASMINOGEN ACTIVATOR INHIBITOR (PAI-1) IN -i(E. COLI)</title><date>1992-02-26</date><risdate>1992</risdate><abstract>L'invention concerne PAI-1 de recombinaison mature et biologiquement fonctionnel exprimée par E. coli, ainsi que des vecteurs d'expression de plasmide pour la production de rPAI-1, ainsi qu'un procédé d'identification d'inhibiteurs de la liaison de PAI-1 et t-PA.
Biologically functional mature E. coli-expressed recombinant PAI-1 is disclosed, as well as plasmid expression vectors for production of rPAI-1, and a method for identifying inhibitors of the binding of PAI-1 and t-PA.</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng ; fre ; ger |
| recordid | cdi_epo_espacenet_EP0471759A1 |
| source | esp@cenet |
| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES USING MICROORGANISMS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS TESTING VINEGAR WINE |
| title | HIGH LEVEL EXPRESSION OF FUNCTIONAL HUMAN PLASMINOGEN ACTIVATOR INHIBITOR (PAI-1) IN -i(E. COLI) |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-03T11%3A40%3A40IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=DAVIS,%20GARY,%20LEE&rft.date=1992-02-26&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EEP0471759A1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |