NOVEL CEPHALOSPORIN INTERMEDIATES AND PROCESS FOR PREPARING THE INTERMEDIATES AND THEIR END PRODUCTS
The present invention provides certain novel cephalosporin derivatives represented by following formula(I), which are especially useful as intermediates for the preparation of cephalosporin compounds possessed with potent and broad antibacterial activities. wherein: R is a C1-4alkyl, C3-4 alkenyl, C...
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creator | KIM, YONG ZU KIM, WON SUP BANG, CHAN SIK YEO, JAE HONG LIM, JONG CHAN |
description | The present invention provides certain novel cephalosporin derivatives represented by following formula(I), which are especially useful as intermediates for the preparation of cephalosporin compounds possessed with potent and broad antibacterial activities. wherein: R is a C1-4alkyl, C3-4 alkenyl, C3-4 cycloalkyl, amino optionally substititued with a C1-4 alkyl radical, or phenyl group optionally subsitututed on its 2-, 4-and/or 6-position with a halogen, C1-4 alkyl, C1-3 alkoxy or hydroxy radical; R is hydrogen or a C1-4 alkyl group; and n is either 0 or 1. The invention also relates to processes for preparing these intermediates and their pharmacologically active cephalosporin antibiotics. |
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The invention also relates to processes for preparing these intermediates and their pharmacologically active cephalosporin antibiotics.</description><edition>5</edition><language>eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>1992</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19920617&DB=EPODOC&CC=EP&NR=0449515A3$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,777,882,25545,76296</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19920617&DB=EPODOC&CC=EP&NR=0449515A3$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>KIM, YONG ZU</creatorcontrib><creatorcontrib>KIM, WON SUP</creatorcontrib><creatorcontrib>BANG, CHAN SIK</creatorcontrib><creatorcontrib>YEO, JAE HONG</creatorcontrib><creatorcontrib>LIM, JONG CHAN</creatorcontrib><title>NOVEL CEPHALOSPORIN INTERMEDIATES AND PROCESS FOR PREPARING THE INTERMEDIATES AND THEIR END PRODUCTS</title><description>The present invention provides certain novel cephalosporin derivatives represented by following formula(I), which are especially useful as intermediates for the preparation of cephalosporin compounds possessed with potent and broad antibacterial activities. wherein: R is a C1-4alkyl, C3-4 alkenyl, C3-4 cycloalkyl, amino optionally substititued with a C1-4 alkyl radical, or phenyl group optionally subsitututed on its 2-, 4-and/or 6-position with a halogen, C1-4 alkyl, C1-3 alkoxy or hydroxy radical; R is hydrogen or a C1-4 alkyl group; and n is either 0 or 1. 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The invention also relates to processes for preparing these intermediates and their pharmacologically active cephalosporin antibiotics.</abstract><edition>5</edition><oa>free_for_read</oa></addata></record> |
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subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
title | NOVEL CEPHALOSPORIN INTERMEDIATES AND PROCESS FOR PREPARING THE INTERMEDIATES AND THEIR END PRODUCTS |
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