COMPOSITIONS AND METHODS FOR DRUG DELIVERY AND CHROMATOGRAPHY

Cyclodextrin derivatives and inclusion complexes having increased solubility and stability are provided. Cyclodextrin derivatives include amino and other modified cyclodextrins, and linked cyclodextrins. Inclusion complexes comprising the foregoing cyclodextrins, and processes for making the cyclode...

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Hauptverfasser: STILE, MARTYN, ALLEN, VAN EYK, STEPHEN, JOHN, MAY, BRUCE, LINDLY, LINCOLN, STEPHEN, FREDERICK, EASTON, CHRISTOPHER, JOHN, WILLIAMS, MICHAEL, LLOYD, SINGH, PARAMJIT, COATES, JOHN, HEWLETT
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creator STILE, MARTYN, ALLEN
VAN EYK, STEPHEN, JOHN
MAY, BRUCE, LINDLY
LINCOLN, STEPHEN, FREDERICK
EASTON, CHRISTOPHER, JOHN
WILLIAMS, MICHAEL, LLOYD
SINGH, PARAMJIT
COATES, JOHN, HEWLETT
description Cyclodextrin derivatives and inclusion complexes having increased solubility and stability are provided. Cyclodextrin derivatives include amino and other modified cyclodextrins, and linked cyclodextrins. Inclusion complexes comprising the foregoing cyclodextrins, and processes for making the cyclodextrin derivatives are disclosed. Also disclosed are cyclodextrin derivatives comprising otherwise substituted or unsubstituted cyclodextrins covalently bonded to agents such as pharmaceuticals. The covalent bond, when broken, yields the agent in active form. Pharmaceutical compositions and methods of treating an animal host are also described, as well as chromatographic compositions and a method for separating racemic mixtures.
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Cyclodextrin derivatives include amino and other modified cyclodextrins, and linked cyclodextrins. Inclusion complexes comprising the foregoing cyclodextrins, and processes for making the cyclodextrin derivatives are disclosed. Also disclosed are cyclodextrin derivatives comprising otherwise substituted or unsubstituted cyclodextrins covalently bonded to agents such as pharmaceuticals. The covalent bond, when broken, yields the agent in active form. Pharmaceutical compositions and methods of treating an animal host are also described, as well as chromatographic compositions and a method for separating racemic mixtures.</abstract><edition>5</edition><oa>free_for_read</oa></addata></record>
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subjects AGRICULTURE
ANIMAL HUSBANDRY
BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES
CHEMISTRY
COMPOSITIONS BASED THEREON
COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
DERIVATIVES THEREOF
FISHING
FORESTRY
HUMAN NECESSITIES
HUNTING
HYGIENE
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC MACROMOLECULAR COMPOUNDS
PEST REPELLANTS OR ATTRACTANTS
PHYSICS
PLANT GROWTH REGULATORS
POLYSACCHARIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF
TESTING
THEIR PREPARATION OR CHEMICAL WORKING-UP
TRAPPING
title COMPOSITIONS AND METHODS FOR DRUG DELIVERY AND CHROMATOGRAPHY
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