Use of a phagocyte-activating agent : LPS or IL-2 for the manufacture of a medicament for treating staphylococcus aureus infection in cows
The present invention relates to methods for treating infectious diseases in animals by initiating qualitative and quantitative changes in the phagocytic cells of said animals. This activation occurs by the administration of a phagocytic-cell activating agent, such as immunomodulators; cytokines suc...
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creator | DALEY, MICHAEL JOSEPH |
description | The present invention relates to methods for treating infectious diseases in animals by initiating qualitative and quantitative changes in the phagocytic cells of said animals. This activation occurs by the administration of a phagocytic-cell activating agent, such as immunomodulators; cytokines such as interleukins (interleukin -1, 2, 3, 4, 5, 6 and 7), interferons and colony stimulating factors; antimicrobials such as mucolytic enzymes, lysozyme, lysostaphin; complement and its components; chemotractants such as lipopolysaccharide and zymosan activated cow sera. The appropriate activation of the phagocytic cells in the animal for effective therapy requires not only an increase in the total number of cells which phagocytose cell particles, but also an increase in the number of particles phagocytosed per cell, intracellular killing. Thus, the present invention also relates to a method for measuring the efficiency of phagocytic-activating agents to predict and monitor appropriate therapy. |
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Thus, the present invention also relates to a method for measuring the efficiency of phagocytic-activating agents to predict and monitor appropriate therapy.</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</subject><subject>MEASURING</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PHYSICS</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>TESTING</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1991</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjTEOgkAQRWksjHqHuQAJgjR2xmA0oSBRazMZZ2ET2Nmwi4YreGpX5QBW_xfv_T-PXlfHIAoQbIO10Og5RvL6gV6bGrBm42ELZXUG6eFUximoUHzD0KEZVGCHflro-K4Ju4_xZXr-jTiPthlbISEaHGAQQmijOByJCQ1Inm4ZzRS2jldTLiI4FJf9MWYrN3YWiQ37W1ElmyTP1vkuzf5A3qxfSxo</recordid><startdate>19910102</startdate><enddate>19910102</enddate><creator>DALEY, MICHAEL JOSEPH</creator><scope>EVB</scope></search><sort><creationdate>19910102</creationdate><title>Use of a phagocyte-activating agent : LPS or IL-2 for the manufacture of a medicament for treating staphylococcus aureus infection in cows</title><author>DALEY, MICHAEL JOSEPH</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_EP0405315A23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre ; ger</language><creationdate>1991</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</topic><topic>MEASURING</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PHYSICS</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>TESTING</topic><toplevel>online_resources</toplevel><creatorcontrib>DALEY, MICHAEL JOSEPH</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>DALEY, MICHAEL JOSEPH</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Use of a phagocyte-activating agent : LPS or IL-2 for the manufacture of a medicament for treating staphylococcus aureus infection in cows</title><date>1991-01-02</date><risdate>1991</risdate><abstract>The present invention relates to methods for treating infectious diseases in animals by initiating qualitative and quantitative changes in the phagocytic cells of said animals. This activation occurs by the administration of a phagocytic-cell activating agent, such as immunomodulators; cytokines such as interleukins (interleukin -1, 2, 3, 4, 5, 6 and 7), interferons and colony stimulating factors; antimicrobials such as mucolytic enzymes, lysozyme, lysostaphin; complement and its components; chemotractants such as lipopolysaccharide and zymosan activated cow sera. The appropriate activation of the phagocytic cells in the animal for effective therapy requires not only an increase in the total number of cells which phagocytose cell particles, but also an increase in the number of particles phagocytosed per cell, intracellular killing. Thus, the present invention also relates to a method for measuring the efficiency of phagocytic-activating agents to predict and monitor appropriate therapy.</abstract><oa>free_for_read</oa></addata></record> |
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subjects | HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEDICAL OR VETERINARY SCIENCE PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES TESTING |
title | Use of a phagocyte-activating agent : LPS or IL-2 for the manufacture of a medicament for treating staphylococcus aureus infection in cows |
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