USE OF ISOCARBACYCLINS FOR PREVENTING OR TREATING ORGAN DISEASES

Pharmaceutical compsns. for the treatment and prophylaxis of intestinal disorders contain a (hetero)isocarbacyclin of formula (I) as active component: (where R1 is H, 1-10C alkyl, -CH2COOR" or a monovalent cation; R" is H or 1-10C alkyl; R2 is H or methyl; R3 is 3-10C alkyl, 3-10C alkenyl,...

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Hauptverfasser: ASANO, SATOSHI 403, FUKIAGE GREEN MANSION, KUROZUMI, SEIZI, TANAKA, TOSHIO, KOYAMA, TAMOTSU, KATO, YOSHINORI, OGAWA, MAKOTO, OHTSU, AKIRA, BANNAI, KIYOSHI, MORI, YOSHIO
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creator ASANO, SATOSHI 403, FUKIAGE GREEN MANSION
KUROZUMI, SEIZI
TANAKA, TOSHIO
KOYAMA, TAMOTSU
KATO, YOSHINORI
OGAWA, MAKOTO
OHTSU, AKIRA
BANNAI, KIYOSHI
MORI, YOSHIO
description Pharmaceutical compsns. for the treatment and prophylaxis of intestinal disorders contain a (hetero)isocarbacyclin of formula (I) as active component: (where R1 is H, 1-10C alkyl, -CH2COOR" or a monovalent cation; R" is H or 1-10C alkyl; R2 is H or methyl; R3 is 3-10C alkyl, 3-10C alkenyl, 3-10C alkynyl, 3-10CG cycloalkyl, (3-10C cycloalkyl)-1-6C alkyl), or phenyl or phenoxy opt. substd. by halogen, OH, 27 2-7C acyloxy, 1-6C alkyl, 1-6C haloalkyl, 1-4C alkoxy, 1-4C haloalkoxy, CN, carboxy or 1-6C alkoxycarbonyl; n is 0 or 1; Q is a gp. of formula -(CH2)4COOR' (II), -CH2-X-CH2CH2COOR' (III), -CH2CH2-Y-CH2COOR' (IV); X and Y are O or S). Des isocarbacyclines, des 4-hétéroisocarbacyclines, des 3-hétéroisocarbacyclines et leurs énantiomères permettent de prévenir ou de traiter efficacement des maladies d'organes tels que le foie ou le rein. Ces composés se caractérisent par le fait qu'ils présentent une forte sélectivité dans l'activité susmentionnée.
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Des isocarbacyclines, des 4-hétéroisocarbacyclines, des 3-hétéroisocarbacyclines et leurs énantiomères permettent de prévenir ou de traiter efficacement des maladies d'organes tels que le foie ou le rein. 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Des isocarbacyclines, des 4-hétéroisocarbacyclines, des 3-hétéroisocarbacyclines et leurs énantiomères permettent de prévenir ou de traiter efficacement des maladies d'organes tels que le foie ou le rein. Ces composés se caractérisent par le fait qu'ils présentent une forte sélectivité dans l'activité susmentionnée.</abstract><oa>free_for_read</oa></addata></record>
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title USE OF ISOCARBACYCLINS FOR PREVENTING OR TREATING ORGAN DISEASES
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