PREPARATION OF T-CELL AND T-CELL MEMBRANE FOR USE IN PREVENTION AND TREATMENT OF AUTOIMMUNE DISEASES

Pharmaceutical preparations are provided for preventing or treating autoimmune diseases in which the active principle is activated T-lymphocyte cells, specific for the autoimmune disease to be treated, which cells have been treated by incubation with a photoactivatable psoralen cross-linking agent,...

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Hauptverfasser: COHEN, IRUN ROBERT, EDELSON, RICHARD L, SHINITZKY, MEIR
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creator COHEN, IRUN ROBERT
EDELSON, RICHARD L
SHINITZKY, MEIR
description Pharmaceutical preparations are provided for preventing or treating autoimmune diseases in which the active principle is activated T-lymphocyte cells, specific for the autoimmune disease to be treated, which cells have been treated by incubation with a photoactivatable psoralen cross-linking agent, such as 8-methoxypsoralen, and then photoactivated. The active principle may also be the membrane fraction of such cells. Such preparations may be formulated into pharmaceutical compositions and administered to prevent or treat autoimmune diseases.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title PREPARATION OF T-CELL AND T-CELL MEMBRANE FOR USE IN PREVENTION AND TREATMENT OF AUTOIMMUNE DISEASES
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