Therapeutic agents

Quinolone sulphonates of formula I in which R1 is lower alkyl; R2 is lower alkyl; and R3, R4 and R5, which may be the same or different, are hydrogen, lower alkyl, lower alkoxy, lower alkylthio, lower alkylsulphinyl, lower alkylsulphonyl, halo, halogenated lower alkyl, halogenated lower alkoxy, cyan...

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Hauptverfasser:	BROWN, MICHAEL DONALD, DAVIES, ROY VICTOR, HOLMAN, NICHOLAS JOHN
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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creator	BROWN, MICHAEL DONALD DAVIES, ROY VICTOR HOLMAN, NICHOLAS JOHN
description	Quinolone sulphonates of formula I in which R1 is lower alkyl; R2 is lower alkyl; and R3, R4 and R5, which may be the same or different, are hydrogen, lower alkyl, lower alkoxy, lower alkylthio, lower alkylsulphinyl, lower alkylsulphonyl, halo, halogenated lower alkyl, halogenated lower alkoxy, cyano, phenyl or phenyl substituted by 1 or 2 groups independently selected from lower alkyl, lower alkoxy and halo, have antihypertensive activity. Processes for preparing compounds of formula I and pharmaceutical compositions containing them are described. Compounds of formula I are also indicated for use in the treatment of heart failure and ischaemic heart disease.
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Processes for preparing compounds of formula I and pharmaceutical compositions containing them are described. 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Processes for preparing compounds of formula I and pharmaceutical compositions containing them are described. 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Processes for preparing compounds of formula I and pharmaceutical compositions containing them are described. Compounds of formula I are also indicated for use in the treatment of heart failure and ischaemic heart disease.</abstract><oa>free_for_read</oa></addata></record>
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language	eng ; fre ; ger
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subjects	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title	Therapeutic agents
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