PROCESS FOR THE PRODUCTION OF 4-NITRO-5-IMIDAZOLYLETHERS AND -THIOETHERS

4-Nitro-5-imidazolyl ethers and thioethers of the formula I (I) where R1 is alkyl, alkoxyalkyl, cycloalkyl, aryl, aralkyl or alkylaryl, R2 is hydrogen, alkyl, cycloalkyl, aryl, aralkyl or alkylaryl, R3 is alkyl, cycloalkyl, aryl, aralkyl, alkylaryl or a heterocyclic or heteroaromatic radical or a co...

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Hauptverfasser: KOEHLER, HERMANN, DOCKNER, TONI
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DOCKNER, TONI
description 4-Nitro-5-imidazolyl ethers and thioethers of the formula I (I) where R1 is alkyl, alkoxyalkyl, cycloalkyl, aryl, aralkyl or alkylaryl, R2 is hydrogen, alkyl, cycloalkyl, aryl, aralkyl or alkylaryl, R3 is alkyl, cycloalkyl, aryl, aralkyl, alkylaryl or a heterocyclic or heteroaromatic radical or a counter-ion of the corresponding alcoholate or thiolate or, where X is sulfur, R3 is hydrogen, and X is oxygen or sulfur, and the stated organic radicals may furthermore carry substituents which are inert under the reaction conditions, are prepared by reacting a dinitroimidazole of the formula II (II) with an alcohol or thiol of the formula III R3-XH (III) in a solvent or diluent at a pH of the from 4 to 16.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title PROCESS FOR THE PRODUCTION OF 4-NITRO-5-IMIDAZOLYLETHERS AND -THIOETHERS
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