A PHARMACEUTICAL COMPOUND CONTAINING NIFEDIPINE

A PHARMACEUTICAL COMPOUND CONTAINING NIFEDIPINE

The invention concerns a pharmaceutical compound containing Nifedipine, combined with a physiologically tolerated substance capable of forming a complex with Nifedipine. This increases the solubility of Nifedipine. The complexing substance is preferably a xanthine, especially Theophylline, which giv...

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Hauptverfasser: RACKUR, HELMUT, KOCH, GUNTHER, DETHLEFSEN, UWE
Format: Patent
Sprache:eng
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CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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creator RACKUR, HELMUT
KOCH, GUNTHER
DETHLEFSEN, UWE
description The invention concerns a pharmaceutical compound containing Nifedipine, combined with a physiologically tolerated substance capable of forming a complex with Nifedipine. This increases the solubility of Nifedipine. The complexing substance is preferably a xanthine, especially Theophylline, which gives a surprising synergistic pharmacological combinatory effect. The invention further concerns a pharmaceutical preparation, especially useful for the Nifedipine/Theophylline combination, and a method for producing such preparations.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title A PHARMACEUTICAL COMPOUND CONTAINING NIFEDIPINE
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