PROCESS FOR THE DETERMINATION OF AN IMMUNOLOGICALLY BINDABLE SUBSTANCE
1. Process for the determination of a bindable analyte according to the principle of heterogeneous immunoassay by incubation of a sample solution which contains the analyte with a labelled first receptor specifically bindable with the analyte and present in dissolved phase and a second receptor pres...
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| creator | KASPAR, KLAUS PETER NAT |
| description | 1. Process for the determination of a bindable analyte according to the principle of heterogeneous immunoassay by incubation of a sample solution which contains the analyte with a labelled first receptor specifically bindable with the analyte and present in dissolved phase and a second receptor present in a solid phase which does not cross-react with the first receptor and can fix a complex which contains the analyte and first receptor, separation of the phases after incubation and quantitative measurement of the labelling bound to the solid phase, characterised in that one determines the back dissociation velocity of the labelling bound to the solid phase into the dissolved phase and uses the quotients of back dissociation velocity and measurement value as measure for the correctness of the test result of the first measurement. |
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Process for the determination of a bindable analyte according to the principle of heterogeneous immunoassay by incubation of a sample solution which contains the analyte with a labelled first receptor specifically bindable with the analyte and present in dissolved phase and a second receptor present in a solid phase which does not cross-react with the first receptor and can fix a complex which contains the analyte and first receptor, separation of the phases after incubation and quantitative measurement of the labelling bound to the solid phase, characterised in that one determines the back dissociation velocity of the labelling bound to the solid phase into the dissolved phase and uses the quotients of back dissociation velocity and measurement value as measure for the correctness of the test result of the first measurement.</description><language>eng ; ger</language><subject>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES ; MEASURING ; PHYSICS ; TESTING</subject><creationdate>1990</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19900221&DB=EPODOC&CC=EP&NR=0227921B1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19900221&DB=EPODOC&CC=EP&NR=0227921B1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>KASPAR, KLAUS PETER NAT</creatorcontrib><title>PROCESS FOR THE DETERMINATION OF AN IMMUNOLOGICALLY BINDABLE SUBSTANCE</title><description>1. 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Process for the determination of a bindable analyte according to the principle of heterogeneous immunoassay by incubation of a sample solution which contains the analyte with a labelled first receptor specifically bindable with the analyte and present in dissolved phase and a second receptor present in a solid phase which does not cross-react with the first receptor and can fix a complex which contains the analyte and first receptor, separation of the phases after incubation and quantitative measurement of the labelling bound to the solid phase, characterised in that one determines the back dissociation velocity of the labelling bound to the solid phase into the dissolved phase and uses the quotients of back dissociation velocity and measurement value as measure for the correctness of the test result of the first measurement.</abstract><oa>free_for_read</oa></addata></record> |
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| language | eng ; ger |
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| subjects | INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING PHYSICS TESTING |
| title | PROCESS FOR THE DETERMINATION OF AN IMMUNOLOGICALLY BINDABLE SUBSTANCE |
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