Tetraenyl prostaglandins
This invention encompasses prostaglandins of the for- mJlawherein R represents hydrogen or lower alkyl having 1 to 6 carbon atoms; R, represents hydrogen, vinyl, or lower alkyl having 1 to 4 carbon atoms and the wavy line represents R or S stereochemistry; R2, R3, and R4 are hydrogen or lower alkyl...
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| creator | GASIECKI, ALAN FRANK COLLINS, PAUL WADDELL |
| description | This invention encompasses prostaglandins of the for- mJlawherein R represents hydrogen or lower alkyl having 1 to 6 carbon atoms; R, represents hydrogen, vinyl, or lower alkyl having 1 to 4 carbon atoms and the wavy line represents R or S stereochemistry; R2, R3, and R4 are hydrogen or lower alkyl having 1 to 4 carbon atoms or R2 and R3 together with carbon Y form a cycloalkenyl having 4 to 6 carbon atoms or R3 and R4 together with carbons X and Y form a cycloalkenyl having 4 to 6 carbons. Compounds of this invention have potent gastric antisecretory and cytoprotective properties with unexpectedly low diarrheogenic side effects. |
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Compounds of this invention have potent gastric antisecretory and cytoprotective properties with unexpectedly low diarrheogenic side effects.</description><edition>4</edition><language>eng ; fre ; ger</language><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS ; CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>1987</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19870603&DB=EPODOC&CC=EP&NR=0224208A2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25544,76293</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19870603&DB=EPODOC&CC=EP&NR=0224208A2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>GASIECKI, ALAN FRANK</creatorcontrib><creatorcontrib>COLLINS, PAUL WADDELL</creatorcontrib><title>Tetraenyl prostaglandins</title><description>This invention encompasses prostaglandins of the for- mJlawherein R represents hydrogen or lower alkyl having 1 to 6 carbon atoms; R, represents hydrogen, vinyl, or lower alkyl having 1 to 4 carbon atoms and the wavy line represents R or S stereochemistry; R2, R3, and R4 are hydrogen or lower alkyl having 1 to 4 carbon atoms or R2 and R3 together with carbon Y form a cycloalkenyl having 4 to 6 carbon atoms or R3 and R4 together with carbons X and Y form a cycloalkenyl having 4 to 6 carbons. Compounds of this invention have potent gastric antisecretory and cytoprotective properties with unexpectedly low diarrheogenic side effects.</description><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS</subject><subject>CHEMISTRY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1987</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZJAISS0pSkzNq8xRKCjKLy5JTM9JzEvJzCvmYWBNS8wpTuWF0twMCm6uIc4euqkF-fGpxQWJyal5qSXxrgEGRkYmRgYWjkbGRCgBAOIDIk4</recordid><startdate>19870603</startdate><enddate>19870603</enddate><creator>GASIECKI, ALAN FRANK</creator><creator>COLLINS, PAUL WADDELL</creator><scope>EVB</scope></search><sort><creationdate>19870603</creationdate><title>Tetraenyl prostaglandins</title><author>GASIECKI, ALAN FRANK ; COLLINS, PAUL WADDELL</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_EP0224208A23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre ; ger</language><creationdate>1987</creationdate><topic>ACYCLIC OR CARBOCYCLIC COMPOUNDS</topic><topic>CHEMISTRY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>GASIECKI, ALAN FRANK</creatorcontrib><creatorcontrib>COLLINS, PAUL WADDELL</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>GASIECKI, ALAN FRANK</au><au>COLLINS, PAUL WADDELL</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Tetraenyl prostaglandins</title><date>1987-06-03</date><risdate>1987</risdate><abstract>This invention encompasses prostaglandins of the for- mJlawherein R represents hydrogen or lower alkyl having 1 to 6 carbon atoms; R, represents hydrogen, vinyl, or lower alkyl having 1 to 4 carbon atoms and the wavy line represents R or S stereochemistry; R2, R3, and R4 are hydrogen or lower alkyl having 1 to 4 carbon atoms or R2 and R3 together with carbon Y form a cycloalkenyl having 4 to 6 carbon atoms or R3 and R4 together with carbons X and Y form a cycloalkenyl having 4 to 6 carbons. Compounds of this invention have potent gastric antisecretory and cytoprotective properties with unexpectedly low diarrheogenic side effects.</abstract><edition>4</edition><oa>free_for_read</oa></addata></record> |
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| language | eng ; fre ; ger |
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| subjects | ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | Tetraenyl prostaglandins |
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