TETRAHYDROPYRIDO (1,2-A) INDOLE DERIVATIVES, PROCESS AND INTERMEDIATES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
A compound of the formula (I) or a pharmaceutically acceptable salt thereof: (I) wherein: R1 is hydrogen, C1-6 alkyl, C1-6 alkoxy or halogen; R2 and R3 are both hydrogen or together represent a bond; R4 is hydrogen and R5 is hydrogen or R4 and R5 together represent an oxo group; R6 is C1-7 alkyl sub...
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creator | THIELKE, DIETRICH HOELTJE, DAGMAR |
description | A compound of the formula (I) or a pharmaceutically acceptable salt thereof: (I) wherein: R1 is hydrogen, C1-6 alkyl, C1-6 alkoxy or halogen; R2 and R3 are both hydrogen or together represent a bond; R4 is hydrogen and R5 is hydrogen or R4 and R5 together represent an oxo group; R6 is C1-7 alkyl substituted by NR8R9 where R8 and R9 are independently hydrogen or C1-4 alkyl or together are C3-7 polymethylene optionally containing a further hetereoatom which is oxygen, sulphur or nitrogen substituted by R10 where R10 is hydrogen, C1-4 alkyl or benzyl, and optionally substituted by one or two C1-4 alkyl, C2-5 alkanoyl, C1-4 alkoxycarbonyl, aminocarbonyl optionally substituted by one or two C1-6 alkyl groups or by a benzyl group, cyano, phenyl or benzyl and wherein any phenyl or benzyl group is optionally substituted in the phenyl ring by one or two halo, CF3, C1-4 alkyl, C1-4 alkoxy, cyano or nitro groups; and R7 is hydrogen or C1-4 alkyl. |
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R2 and R3 are both hydrogen or together represent a bond; R4 is hydrogen and R5 is hydrogen or R4 and R5 together represent an oxo group; R6 is C1-7 alkyl substituted by NR8R9 where R8 and R9 are independently hydrogen or C1-4 alkyl or together are C3-7 polymethylene optionally containing a further hetereoatom which is oxygen, sulphur or nitrogen substituted by R10 where R10 is hydrogen, C1-4 alkyl or benzyl, and optionally substituted by one or two C1-4 alkyl, C2-5 alkanoyl, C1-4 alkoxycarbonyl, aminocarbonyl optionally substituted by one or two C1-6 alkyl groups or by a benzyl group, cyano, phenyl or benzyl and wherein any phenyl or benzyl group is optionally substituted in the phenyl ring by one or two halo, CF3, C1-4 alkyl, C1-4 alkoxy, cyano or nitro groups; and R7 is hydrogen or C1-4 alkyl.</description><language>eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; 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R2 and R3 are both hydrogen or together represent a bond; R4 is hydrogen and R5 is hydrogen or R4 and R5 together represent an oxo group; R6 is C1-7 alkyl substituted by NR8R9 where R8 and R9 are independently hydrogen or C1-4 alkyl or together are C3-7 polymethylene optionally containing a further hetereoatom which is oxygen, sulphur or nitrogen substituted by R10 where R10 is hydrogen, C1-4 alkyl or benzyl, and optionally substituted by one or two C1-4 alkyl, C2-5 alkanoyl, C1-4 alkoxycarbonyl, aminocarbonyl optionally substituted by one or two C1-6 alkyl groups or by a benzyl group, cyano, phenyl or benzyl and wherein any phenyl or benzyl group is optionally substituted in the phenyl ring by one or two halo, CF3, C1-4 alkyl, C1-4 alkoxy, cyano or nitro groups; and R7 is hydrogen or C1-4 alkyl.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1991</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNizEKwkAQRdNYiHqHKRUSMAoBy3F3NANmd5kdBasQZK1EBT2GhzaKB7D6fN57w-ylpIL10YoPR2HrYVrmiwJnwM76HYEl4QMqHyjmEMQbihHQ2Z4rSUOWUSnCxgtoTSy9QwGlL7z7eqFGadDQXtngDoxvgo_8wbE_TpEdu-0nbsbZ4NxdHmny21EGG1JTF-l-a9Pj3p3SNT1bCvNFuaxW1bpc_qG8AcmxPyg</recordid><startdate>19910123</startdate><enddate>19910123</enddate><creator>THIELKE, DIETRICH</creator><creator>HOELTJE, DAGMAR</creator><scope>EVB</scope></search><sort><creationdate>19910123</creationdate><title>TETRAHYDROPYRIDO (1,2-A) INDOLE DERIVATIVES, PROCESS AND INTERMEDIATES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM</title><author>THIELKE, DIETRICH ; HOELTJE, DAGMAR</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_EP0213696B13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>1991</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>THIELKE, DIETRICH</creatorcontrib><creatorcontrib>HOELTJE, DAGMAR</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>THIELKE, DIETRICH</au><au>HOELTJE, DAGMAR</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>TETRAHYDROPYRIDO (1,2-A) INDOLE DERIVATIVES, PROCESS AND INTERMEDIATES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM</title><date>1991-01-23</date><risdate>1991</risdate><abstract>A compound of the formula (I) or a pharmaceutically acceptable salt thereof: (I) wherein: R1 is hydrogen, C1-6 alkyl, C1-6 alkoxy or halogen; R2 and R3 are both hydrogen or together represent a bond; R4 is hydrogen and R5 is hydrogen or R4 and R5 together represent an oxo group; R6 is C1-7 alkyl substituted by NR8R9 where R8 and R9 are independently hydrogen or C1-4 alkyl or together are C3-7 polymethylene optionally containing a further hetereoatom which is oxygen, sulphur or nitrogen substituted by R10 where R10 is hydrogen, C1-4 alkyl or benzyl, and optionally substituted by one or two C1-4 alkyl, C2-5 alkanoyl, C1-4 alkoxycarbonyl, aminocarbonyl optionally substituted by one or two C1-6 alkyl groups or by a benzyl group, cyano, phenyl or benzyl and wherein any phenyl or benzyl group is optionally substituted in the phenyl ring by one or two halo, CF3, C1-4 alkyl, C1-4 alkoxy, cyano or nitro groups; and R7 is hydrogen or C1-4 alkyl.</abstract><oa>free_for_read</oa></addata></record> |
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subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
title | TETRAHYDROPYRIDO (1,2-A) INDOLE DERIVATIVES, PROCESS AND INTERMEDIATES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
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