TETRAHYDROPYRIDO (1,2-A) INDOLE DERIVATIVES, PROCESS AND INTERMEDIATES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

A compound of the formula (I) or a pharmaceutically acceptable salt thereof: (I) wherein: R1 is hydrogen, C1-6 alkyl, C1-6 alkoxy or halogen; R2 and R3 are both hydrogen or together represent a bond; R4 is hydrogen and R5 is hydrogen or R4 and R5 together represent an oxo group; R6 is C1-7 alkyl sub...

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Hauptverfasser: THIELKE, DIETRICH, HOELTJE, DAGMAR
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creator THIELKE, DIETRICH
HOELTJE, DAGMAR
description A compound of the formula (I) or a pharmaceutically acceptable salt thereof: (I) wherein: R1 is hydrogen, C1-6 alkyl, C1-6 alkoxy or halogen; R2 and R3 are both hydrogen or together represent a bond; R4 is hydrogen and R5 is hydrogen or R4 and R5 together represent an oxo group; R6 is C1-7 alkyl substituted by NR8R9 where R8 and R9 are independently hydrogen or C1-4 alkyl or together are C3-7 polymethylene optionally containing a further hetereoatom which is oxygen, sulphur or nitrogen substituted by R10 where R10 is hydrogen, C1-4 alkyl or benzyl, and optionally substituted by one or two C1-4 alkyl, C2-5 alkanoyl, C1-4 alkoxycarbonyl, aminocarbonyl optionally substituted by one or two C1-6 alkyl groups or by a benzyl group, cyano, phenyl or benzyl and wherein any phenyl or benzyl group is optionally substituted in the phenyl ring by one or two halo, CF3, C1-4 alkyl, C1-4 alkoxy, cyano or nitro groups; and R7 is hydrogen or C1-4 alkyl.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title TETRAHYDROPYRIDO (1,2-A) INDOLE DERIVATIVES, PROCESS AND INTERMEDIATES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
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