SMALL PARTICLE FORMATION AND ENCAPSULATION

Un procédé de formation et d'enrobage simultanés de petites particules d'un composé à partir d'une solution comprend: (a) la dissolution dudit composé dans un premier solvant; (b) la préparation d'une solution de matériau d'enrobage et d'un électrolyte dans un deuxième...

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Hauptverfasser: DING, SHULIN, FRANK, SYLVAN, GERALD, BRODIN, ARNE, FOLKE
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FRANK, SYLVAN, GERALD
BRODIN, ARNE, FOLKE
description Un procédé de formation et d'enrobage simultanés de petites particules d'un composé à partir d'une solution comprend: (a) la dissolution dudit composé dans un premier solvant; (b) la préparation d'une solution de matériau d'enrobage et d'un électrolyte dans un deuxième solvant miscible avec le premier solvant et dans lequel le composé à enrober est plus ou moins insoluble, en une quantité utile, mais juste insuffisante pour provoquer la coacervation du matériau d'enrobage sans interagir avec lui; (c) le mélange des solutions des étapes (a) et (b), et leur agitation pour la précipitation du composé sous forme de petites particules et la formation simultanée d'un coacervé du matériau d'enrobage; et (d) la gélatinisation du matériau d'enrobage. Process for the formation and the simultaneous encapsulation of small particles of a compound from solution which comprises: (a) dissolving said compound in a first solvent; (b) preparing a solution of encapsulating material and an electrolyte in a second solvent which is miscible with the first solvent and in which the compound to be encapsulated is more or less insoluble, in an amount which is effective, but present in an amount just insufficient to cause coacervation of the encapsulating material without interacting with it; (c) mixing the solutions from step (a) and (b) while stirring to cause the concurrent precipitation of the compound as small particles and formation of a coacervate of the encapsulating material; and (d) gelling the encapsulating material.
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Process for the formation and the simultaneous encapsulation of small particles of a compound from solution which comprises: (a) dissolving said compound in a first solvent; (b) preparing a solution of encapsulating material and an electrolyte in a second solvent which is miscible with the first solvent and in which the compound to be encapsulated is more or less insoluble, in an amount which is effective, but present in an amount just insufficient to cause coacervation of the encapsulating material without interacting with it; (c) mixing the solutions from step (a) and (b) while stirring to cause the concurrent precipitation of the compound as small particles and formation of a coacervate of the encapsulating material; and (d) gelling the encapsulating material.</abstract><edition>4</edition><oa>free_for_read</oa></addata></record>
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language eng ; fre ; ger
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subjects BABY COMFORTERS
CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY
CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICALPURPOSES
DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY
DEVICES FOR RECEIVING SPITTLE
DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGINGPHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL ORADMINISTERING FORMS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PERFORMING OPERATIONS
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
THEIR RELEVANT APPARATUS
TRANSPORTING
title SMALL PARTICLE FORMATION AND ENCAPSULATION
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