PREPARATION OF PEPTIDE SUBSTRATES FOR VIRUS-SPECIFIED PROTEASES

Specific tetrapeptide substrates are disclosed which comprise a C-terminal indicator group linked by an amide or ester linkage to peptide sequences resembling Picornavirus protease cleavage recognition sites. Such substrates may be used to detect the activity of the corresponding virus-specified pro...

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Bibliographische Detailangaben
Hauptverfasser:	KETTNER, CHARLES ADRIAN, KORANT, BRUCE DAVID
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES OF PREPARING SUCH COMPOSITIONS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	Specific tetrapeptide substrates are disclosed which comprise a C-terminal indicator group linked by an amide or ester linkage to peptide sequences resembling Picornavirus protease cleavage recognition sites. Such substrates may be used to detect the activity of the corresponding virus-specified protease.