Antitumor composition
An antitumor composition was prepared by admixing a 5-fluorohexahydropyrimidine of the formula (I) wherein R is a lower alkyl group and R is a hydrogen atom or a lower alkyl group, and a pyrimidine nucleic acid base and/or the riboside thereof. Thus, the antitumor activity of the 5-fluorohexahydropy...
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| creator | OKUTANI, TETSUYA OOTSU, KOICHIRO |
| description | An antitumor composition was prepared by admixing a 5-fluorohexahydropyrimidine of the formula (I) wherein R is a lower alkyl group and R is a hydrogen atom or a lower alkyl group, and a pyrimidine nucleic acid base and/or the riboside thereof. Thus, the antitumor activity of the 5-fluorohexahydropyrimidine of the formula (I) is remarkably increased by the joint use of a pyrimidine nucleic acid base and/or the riboside thereof, which has little antitumor activity. |
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Thus, the antitumor activity of the 5-fluorohexahydropyrimidine of the formula (I) is remarkably increased by the joint use of a pyrimidine nucleic acid base and/or the riboside thereof, which has little antitumor activity.</description><edition>4</edition><language>eng ; fre ; ger</language><subject>CHEMISTRY ; DERIVATIVES THEREOF ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; NUCLEIC ACIDS ; NUCLEOSIDES ; NUCLEOTIDES ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS ; SUGARS</subject><creationdate>1986</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19860219&DB=EPODOC&CC=EP&NR=0171942A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,777,882,25545,76296</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19860219&DB=EPODOC&CC=EP&NR=0171942A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>OKUTANI, TETSUYA</creatorcontrib><creatorcontrib>OOTSU, KOICHIRO</creatorcontrib><title>Antitumor composition</title><description>An antitumor composition was prepared by admixing a 5-fluorohexahydropyrimidine of the formula (I) wherein R is a lower alkyl group and R is a hydrogen atom or a lower alkyl group, and a pyrimidine nucleic acid base and/or the riboside thereof. 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Thus, the antitumor activity of the 5-fluorohexahydropyrimidine of the formula (I) is remarkably increased by the joint use of a pyrimidine nucleic acid base and/or the riboside thereof, which has little antitumor activity.</abstract><edition>4</edition><oa>free_for_read</oa></addata></record> |
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| language | eng ; fre ; ger |
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| subjects | CHEMISTRY DERIVATIVES THEREOF HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SUGARS |
| title | Antitumor composition |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-18T09%3A38%3A24IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=OKUTANI,%20TETSUYA&rft.date=1986-02-19&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EEP0171942A1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |