Antitumor composition

An antitumor composition was prepared by admixing a 5-fluorohexahydropyrimidine of the formula (I) wherein R is a lower alkyl group and R is a hydrogen atom or a lower alkyl group, and a pyrimidine nucleic acid base and/or the riboside thereof. Thus, the antitumor activity of the 5-fluorohexahydropy...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	OKUTANI, TETSUYA, OOTSU, KOICHIRO
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMISTRY DERIVATIVES THEREOF HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SUGARS
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Beschreibung
Zusammenfassung:	An antitumor composition was prepared by admixing a 5-fluorohexahydropyrimidine of the formula (I) wherein R is a lower alkyl group and R is a hydrogen atom or a lower alkyl group, and a pyrimidine nucleic acid base and/or the riboside thereof. Thus, the antitumor activity of the 5-fluorohexahydropyrimidine of the formula (I) is remarkably increased by the joint use of a pyrimidine nucleic acid base and/or the riboside thereof, which has little antitumor activity.