ENZYME-PROTEIN CONJUGATE, PROCESS FOR ITS PREPARATION AND PHARMACEUTICAL USE THEREOF

1. A compound of formula II: in which X is an acyl group of formula -R - @ - wherein R is an aliphatic or aromatic residue, A is a bridging group comprising at least one heteroatom selected from oxygen sulphur and nitrogen, in which the nitrogen is optionally substituted by C1-6 alkyl, B is a hydrop...

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Bibliographische Detailangaben
1. Verfasser:	SMITH, RICHARD ANTHONY GODWIN
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	1. A compound of formula II: in which X is an acyl group of formula -R - @ - wherein R is an aliphatic or aromatic residue, A is a bridging group comprising at least one heteroatom selected from oxygen sulphur and nitrogen, in which the nitrogen is optionally substituted by C1-6 alkyl, B is a hydrophilic linking group, and W represents a group capable of reacting directly with the amino acid side chain of a protein or protein attachment group, Z is a counter anion and R1 to R4 are each independently hydrogen or an electron withdrawing moiety.