ANTIHYPERTENSIVE N-PIPERAZINYLALKANOYLANILIDES

N-piperazinylalkanoylanilides of formulawherein is O, 1 or2, each of Rand R, is H or alkyl, and each of R2, R3 and R4 is H, halogen, alkyl, hydroxy-alkyl, alkoxy, aralkoxy, alkylthio, aralkylthio, alkylsulphonyl, alkylsulphenyl, NO2, NH2, alkylamino, acylamino, ureido, alkylureido, alkylsulphonylami...

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Hauptverfasser:	CATTO, ALBERTO, NARDI, DANTE, GRAZIANI, GABRIELE, LEONARDI, AMEDEO
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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creator	CATTO, ALBERTO NARDI, DANTE GRAZIANI, GABRIELE LEONARDI, AMEDEO
description	N-piperazinylalkanoylanilides of formulawherein is O, 1 or2, each of Rand R, is H or alkyl, and each of R2, R3 and R4 is H, halogen, alkyl, hydroxy-alkyl, alkoxy, aralkoxy, alkylthio, aralkylthio, alkylsulphonyl, alkylsulphenyl, NO2, NH2, alkylamino, acylamino, ureido, alkylureido, alkylsulphonylamino, CF3, acyl, CN, COOH, alkoxycarbonyl, NH2CO, SO3H, guanidinosulphonyl, NH2COO, OH, acyloxy, alkylsulphonyloxy, alkylenedioxy or SO2NR5R6 wherein each of R5 and R6 is H, alkyl, aryl or acyl, and their pharmaceutically acceptable acid addition salts, are antihypertensive agents.They may be prepared by condensing 1-(2-methoxyphenyl)- -piperazine with an alkanoylanilide of formula
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NARDI, DANTE ; GRAZIANI, GABRIELE ; LEONARDI, AMEDEO</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_EP0120558B13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>1989</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>CATTO, ALBERTO</creatorcontrib><creatorcontrib>NARDI, DANTE</creatorcontrib><creatorcontrib>GRAZIANI, GABRIELE</creatorcontrib><creatorcontrib>LEONARDI, AMEDEO</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>CATTO, ALBERTO</au><au>NARDI, DANTE</au><au>GRAZIANI, GABRIELE</au><au>LEONARDI, AMEDEO</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>ANTIHYPERTENSIVE N-PIPERAZINYLALKANOYLANILIDES</title><date>1989-03-08</date><risdate>1989</risdate><abstract>N-piperazinylalkanoylanilides of formulawherein is O, 1 or2, each of Rand R, is H or alkyl, and each of R2, R3 and R4 is H, halogen, alkyl, hydroxy-alkyl, alkoxy, aralkoxy, alkylthio, aralkylthio, alkylsulphonyl, alkylsulphenyl, NO2, NH2, alkylamino, acylamino, ureido, alkylureido, alkylsulphonylamino, CF3, acyl, CN, COOH, alkoxycarbonyl, NH2CO, SO3H, guanidinosulphonyl, NH2COO, OH, acyloxy, alkylsulphonyloxy, alkylenedioxy or SO2NR5R6 wherein each of R5 and R6 is H, alkyl, aryl or acyl, and their pharmaceutically acceptable acid addition salts, are antihypertensive agents.They may be prepared by condensing 1-(2-methoxyphenyl)- -piperazine with an alkanoylanilide of formula</abstract><edition>4</edition><oa>free_for_read</oa></addata></record>
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subjects	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title	ANTIHYPERTENSIVE N-PIPERAZINYLALKANOYLANILIDES
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