FLUORINATED CYCLIC HEXAPEPTIDE SOMATOSTATIN ANALOGS, PROCESS FOR THEIR PREPARATION, INTERMEDIATE PRODUCTS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Fluorinated somatostatin analogs are prepared wherein a cyclic hexapeptide contains a secondary amino acid which replaces seven of the ring amino acids of somatostatin and the Lys side chain is monofluorinated in the γ or 8 positions. The cyclic hexapeptides are easier to synthesize, have a longer d...

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Bibliographische Detailangaben
Hauptverfasser: CURLEY, PAUL E, HIRSCHMANN, RALPH F
Format: Patent
Sprache:eng
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