Pharmaceutically active copolymers, process for their preparation and pharmaceutical compositions containing them
The invention relates to new, pharmaceutically active copolymers with heparin-like activity, pharmaceutically acceptable salts thereof and a process for their preparation. The new copolymers comprising the units of the general formula /I/derived from /meth/acrylic acid or an ester thereof /X stands...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng ; fre ; ger |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | KARPATI, EGON LOW, MIKLOS GYORGYI, JUDIT STPORNY, LASZLO NAGY, MIKLOS KISFALUDY, LAJOS HORVATH, ISTVAN MACHOVICH, RAYMUND CSOMOR, KATALIN |
| description | The invention relates to new, pharmaceutically active copolymers with heparin-like activity, pharmaceutically acceptable salts thereof and a process for their preparation. The new copolymers comprising the units of the general formula /I/derived from /meth/acrylic acid or an ester thereof /X stands for hydrogen or methyl and Y is hydrogen/, units of the formula /III/optionally units of the general formula /II//Z' is hydrogen/, and chain terminating units, formed from the units of the formulae /I/, /III/ and optionally /II/ under the conditions of copolymerization, in a statistical arrangement, and the pharmaceutically acceptable salts thereof, which contain, in addition to the above chain-members, units of the general formulae /IV/ and/or /V//X has the same meaning as defined above, and A is a cation/ satisfactorily replace the organogenic heparin, or give a synergistic combination with that. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_EP0093489A2</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>EP0093489A2</sourcerecordid><originalsourceid>FETCH-epo_espacenet_EP0093489A23</originalsourceid><addsrcrecordid>eNqNjL8KwjAQxrM4iPoO9wAKxTrYUaTi2MG9HPFqA0nuzEWhb28KLm5OH9-f37c0z27EFNDSKzuL3k-ANrs3gWVhPwVKugVJbEkVBk6QR3KpJCSYMDuOgPEO8vNS4CCsbq61mJjRRRcfMxzWZjGgV9p8dWXg0t7O1x0J96RSXiLlvu2qqqkPx-a0r_-YfADwcUTd</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Pharmaceutically active copolymers, process for their preparation and pharmaceutical compositions containing them</title><source>esp@cenet</source><creator>KARPATI, EGON ; LOW, MIKLOS ; GYORGYI, JUDIT ; STPORNY, LASZLO ; NAGY, MIKLOS ; KISFALUDY, LAJOS ; HORVATH, ISTVAN ; MACHOVICH, RAYMUND ; CSOMOR, KATALIN</creator><creatorcontrib>KARPATI, EGON ; LOW, MIKLOS ; GYORGYI, JUDIT ; STPORNY, LASZLO ; NAGY, MIKLOS ; KISFALUDY, LAJOS ; HORVATH, ISTVAN ; MACHOVICH, RAYMUND ; CSOMOR, KATALIN</creatorcontrib><description>The invention relates to new, pharmaceutically active copolymers with heparin-like activity, pharmaceutically acceptable salts thereof and a process for their preparation. The new copolymers comprising the units of the general formula /I/derived from /meth/acrylic acid or an ester thereof /X stands for hydrogen or methyl and Y is hydrogen/, units of the formula /III/optionally units of the general formula /II//Z' is hydrogen/, and chain terminating units, formed from the units of the formulae /I/, /III/ and optionally /II/ under the conditions of copolymerization, in a statistical arrangement, and the pharmaceutically acceptable salts thereof, which contain, in addition to the above chain-members, units of the general formulae /IV/ and/or /V//X has the same meaning as defined above, and A is a cation/ satisfactorily replace the organogenic heparin, or give a synergistic combination with that.</description><language>eng ; fre ; ger</language><subject>CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES ; CHEMISTRY ; COMPOSITIONS BASED THEREON ; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR ; HUMAN NECESSITIES ; HYGIENE ; MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVINGCARBON-TO-CARBON UNSATURATED BONDS ; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL ; ORGANIC MACROMOLECULAR COMPOUNDS ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS ; THEIR PREPARATION OR CHEMICAL WORKING-UP</subject><creationdate>1983</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19831109&DB=EPODOC&CC=EP&NR=0093489A2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19831109&DB=EPODOC&CC=EP&NR=0093489A2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>KARPATI, EGON</creatorcontrib><creatorcontrib>LOW, MIKLOS</creatorcontrib><creatorcontrib>GYORGYI, JUDIT</creatorcontrib><creatorcontrib>STPORNY, LASZLO</creatorcontrib><creatorcontrib>NAGY, MIKLOS</creatorcontrib><creatorcontrib>KISFALUDY, LAJOS</creatorcontrib><creatorcontrib>HORVATH, ISTVAN</creatorcontrib><creatorcontrib>MACHOVICH, RAYMUND</creatorcontrib><creatorcontrib>CSOMOR, KATALIN</creatorcontrib><title>Pharmaceutically active copolymers, process for their preparation and pharmaceutical compositions containing them</title><description>The invention relates to new, pharmaceutically active copolymers with heparin-like activity, pharmaceutically acceptable salts thereof and a process for their preparation. The new copolymers comprising the units of the general formula /I/derived from /meth/acrylic acid or an ester thereof /X stands for hydrogen or methyl and Y is hydrogen/, units of the formula /III/optionally units of the general formula /II//Z' is hydrogen/, and chain terminating units, formed from the units of the formulae /I/, /III/ and optionally /II/ under the conditions of copolymerization, in a statistical arrangement, and the pharmaceutically acceptable salts thereof, which contain, in addition to the above chain-members, units of the general formulae /IV/ and/or /V//X has the same meaning as defined above, and A is a cation/ satisfactorily replace the organogenic heparin, or give a synergistic combination with that.</description><subject>CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS BASED THEREON</subject><subject>DISINFECTION, STERILISATION, OR DEODORISATION OF AIR</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVINGCARBON-TO-CARBON UNSATURATED BONDS</subject><subject>MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL</subject><subject>ORGANIC MACROMOLECULAR COMPOUNDS</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><subject>THEIR PREPARATION OR CHEMICAL WORKING-UP</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1983</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjL8KwjAQxrM4iPoO9wAKxTrYUaTi2MG9HPFqA0nuzEWhb28KLm5OH9-f37c0z27EFNDSKzuL3k-ANrs3gWVhPwVKugVJbEkVBk6QR3KpJCSYMDuOgPEO8vNS4CCsbq61mJjRRRcfMxzWZjGgV9p8dWXg0t7O1x0J96RSXiLlvu2qqqkPx-a0r_-YfADwcUTd</recordid><startdate>19831109</startdate><enddate>19831109</enddate><creator>KARPATI, EGON</creator><creator>LOW, MIKLOS</creator><creator>GYORGYI, JUDIT</creator><creator>STPORNY, LASZLO</creator><creator>NAGY, MIKLOS</creator><creator>KISFALUDY, LAJOS</creator><creator>HORVATH, ISTVAN</creator><creator>MACHOVICH, RAYMUND</creator><creator>CSOMOR, KATALIN</creator><scope>EVB</scope></search><sort><creationdate>19831109</creationdate><title>Pharmaceutically active copolymers, process for their preparation and pharmaceutical compositions containing them</title><author>KARPATI, EGON ; LOW, MIKLOS ; GYORGYI, JUDIT ; STPORNY, LASZLO ; NAGY, MIKLOS ; KISFALUDY, LAJOS ; HORVATH, ISTVAN ; MACHOVICH, RAYMUND ; CSOMOR, KATALIN</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_EP0093489A23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre ; ger</language><creationdate>1983</creationdate><topic>CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS BASED THEREON</topic><topic>DISINFECTION, STERILISATION, OR DEODORISATION OF AIR</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVINGCARBON-TO-CARBON UNSATURATED BONDS</topic><topic>MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL</topic><topic>ORGANIC MACROMOLECULAR COMPOUNDS</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><topic>THEIR PREPARATION OR CHEMICAL WORKING-UP</topic><toplevel>online_resources</toplevel><creatorcontrib>KARPATI, EGON</creatorcontrib><creatorcontrib>LOW, MIKLOS</creatorcontrib><creatorcontrib>GYORGYI, JUDIT</creatorcontrib><creatorcontrib>STPORNY, LASZLO</creatorcontrib><creatorcontrib>NAGY, MIKLOS</creatorcontrib><creatorcontrib>KISFALUDY, LAJOS</creatorcontrib><creatorcontrib>HORVATH, ISTVAN</creatorcontrib><creatorcontrib>MACHOVICH, RAYMUND</creatorcontrib><creatorcontrib>CSOMOR, KATALIN</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>KARPATI, EGON</au><au>LOW, MIKLOS</au><au>GYORGYI, JUDIT</au><au>STPORNY, LASZLO</au><au>NAGY, MIKLOS</au><au>KISFALUDY, LAJOS</au><au>HORVATH, ISTVAN</au><au>MACHOVICH, RAYMUND</au><au>CSOMOR, KATALIN</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Pharmaceutically active copolymers, process for their preparation and pharmaceutical compositions containing them</title><date>1983-11-09</date><risdate>1983</risdate><abstract>The invention relates to new, pharmaceutically active copolymers with heparin-like activity, pharmaceutically acceptable salts thereof and a process for their preparation. The new copolymers comprising the units of the general formula /I/derived from /meth/acrylic acid or an ester thereof /X stands for hydrogen or methyl and Y is hydrogen/, units of the formula /III/optionally units of the general formula /II//Z' is hydrogen/, and chain terminating units, formed from the units of the formulae /I/, /III/ and optionally /II/ under the conditions of copolymerization, in a statistical arrangement, and the pharmaceutically acceptable salts thereof, which contain, in addition to the above chain-members, units of the general formulae /IV/ and/or /V//X has the same meaning as defined above, and A is a cation/ satisfactorily replace the organogenic heparin, or give a synergistic combination with that.</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng ; fre ; ger |
| recordid | cdi_epo_espacenet_EP0093489A2 |
| source | esp@cenet |
| subjects | CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES CHEMISTRY COMPOSITIONS BASED THEREON DISINFECTION, STERILISATION, OR DEODORISATION OF AIR HUMAN NECESSITIES HYGIENE MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVINGCARBON-TO-CARBON UNSATURATED BONDS MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES MEDICAL OR VETERINARY SCIENCE METALLURGY METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL ORGANIC MACROMOLECULAR COMPOUNDS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS THEIR PREPARATION OR CHEMICAL WORKING-UP |
| title | Pharmaceutically active copolymers, process for their preparation and pharmaceutical compositions containing them |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-06T09%3A36%3A36IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=KARPATI,%20EGON&rft.date=1983-11-09&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EEP0093489A2%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |