2,4,6-TRIIODO-ISOPHTHALAMIC ACID DERIVATIVES, THEIR PREPARATION AND X-RAY CONTRAST AGENTS BASED ON THESE COMPOUNDS

Compounds of the formula wherein R1 is C1-4 alkyl, C1-4 alkyl substituted by OH or C1-2 alkoxy; R2, R3 and R4 are independently each hydrogen or C1-4 alkyl; Z is -A-NHCH3 or when R1 is hydroxy or alkoxy substituted alkyl and/or when R3 is lower alkyl, Z can also be hydroxy-C2-5-alkylamino; R5 is C1-...

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Hauptverfasser:	KLIEGER, ERICH, MUTZEL, WOLFGANG
Format:	Patent
Sprache:	eng ; ger
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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creator	KLIEGER, ERICH MUTZEL, WOLFGANG
description	Compounds of the formula wherein R1 is C1-4 alkyl, C1-4 alkyl substituted by OH or C1-2 alkoxy; R2, R3 and R4 are independently each hydrogen or C1-4 alkyl; Z is -A-NHCH3 or when R1 is hydroxy or alkoxy substituted alkyl and/or when R3 is lower alkyl, Z can also be hydroxy-C2-5-alkylamino; R5 is C1-4 alkyl or C1-4 alkyl substituted by OH; n is 1, 2 or 3; and A is: wherein R7 is H or C1-4 alkyl; R8 is H, C1-4 alkyl or C1-4 alkyl substituted by OH or C1-2 alkoxy; or together R7 and R8 form a propylene or hydroxypropylene ring; and m is 0 or 1; or an ester thereof with a C1-C4 alkanol or a physiologically acceptable salt thereof with a base, are valuable as X-ray contrast media.
format	Patent
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R2, R3 and R4 are independently each hydrogen or C1-4 alkyl; Z is -A-NHCH3 or when R1 is hydroxy or alkoxy substituted alkyl and/or when R3 is lower alkyl, Z can also be hydroxy-C2-5-alkylamino; R5 is C1-4 alkyl or C1-4 alkyl substituted by OH; n is 1, 2 or 3; and A is: wherein R7 is H or C1-4 alkyl; R8 is H, C1-4 alkyl or C1-4 alkyl substituted by OH or C1-2 alkoxy; or together R7 and R8 form a propylene or hydroxypropylene ring; and m is 0 or 1; or an ester thereof with a C1-C4 alkanol or a physiologically acceptable salt thereof with a base, are valuable as X-ray contrast media.</description><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS</subject><subject>CHEMISTRY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1982</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNi0EKwjAQRbtxIeod5gANtFpEl9NktAGbhGQsuipF4kq0WO-PWXgAVx_ee3-evdd5lW8Fe62tskIH6xpu8IStloBSK1DkdYesOwo5cEPag_Pk0CdmDaBRcBEeryCtYY-BAY9kOECNgRSkJJ0CJd06ezYqLLPZfXhMcfXbRQYHYtmIOL76OI3DLT7jpydXFGW5q_Z1ufkj-QKGUDeE</recordid><startdate>19820519</startdate><enddate>19820519</enddate><creator>KLIEGER, ERICH</creator><creator>MUTZEL, WOLFGANG</creator><scope>EVB</scope></search><sort><creationdate>19820519</creationdate><title>2,4,6-TRIIODO-ISOPHTHALAMIC ACID DERIVATIVES, THEIR PREPARATION AND X-RAY CONTRAST AGENTS BASED ON THESE COMPOUNDS</title><author>KLIEGER, ERICH ; MUTZEL, WOLFGANG</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_EP0011849B13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; ger</language><creationdate>1982</creationdate><topic>ACYCLIC OR CARBOCYCLIC COMPOUNDS</topic><topic>CHEMISTRY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><toplevel>online_resources</toplevel><creatorcontrib>KLIEGER, ERICH</creatorcontrib><creatorcontrib>MUTZEL, WOLFGANG</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>KLIEGER, ERICH</au><au>MUTZEL, WOLFGANG</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>2,4,6-TRIIODO-ISOPHTHALAMIC ACID DERIVATIVES, THEIR PREPARATION AND X-RAY CONTRAST AGENTS BASED ON THESE COMPOUNDS</title><date>1982-05-19</date><risdate>1982</risdate><abstract>Compounds of the formula wherein R1 is C1-4 alkyl, C1-4 alkyl substituted by OH or C1-2 alkoxy; R2, R3 and R4 are independently each hydrogen or C1-4 alkyl; Z is -A-NHCH3 or when R1 is hydroxy or alkoxy substituted alkyl and/or when R3 is lower alkyl, Z can also be hydroxy-C2-5-alkylamino; R5 is C1-4 alkyl or C1-4 alkyl substituted by OH; n is 1, 2 or 3; and A is: wherein R7 is H or C1-4 alkyl; R8 is H, C1-4 alkyl or C1-4 alkyl substituted by OH or C1-2 alkoxy; or together R7 and R8 form a propylene or hydroxypropylene ring; and m is 0 or 1; or an ester thereof with a C1-C4 alkanol or a physiologically acceptable salt thereof with a base, are valuable as X-ray contrast media.</abstract><oa>free_for_read</oa></addata></record>
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language	eng ; ger
recordid	cdi_epo_espacenet_EP0011849B1
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subjects	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title	2,4,6-TRIIODO-ISOPHTHALAMIC ACID DERIVATIVES, THEIR PREPARATION AND X-RAY CONTRAST AGENTS BASED ON THESE COMPOUNDS
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