ANTICUERPOS ANTI ALFA-SINUCLEÍNA
La presente invención se refiere a anticuerpos que se unen a alfa sinucleína y fragmentos de la misma capaces de unirse a alfa sinucleína como un monómero y en fibrillas y prevenir la agregación de alfa sinucleína inducida por fibrillas de alfa sinucleína. Los anticuerpos de la presente invención so...
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| creator | ADAMS, Ralph LIGHTWOOD, Daniel John BAKER, Terence Seward DE LICHTERVELDE, Lorenzo TYSON, Kerry Louise MCMILLAN, David James DOWNEY, Patrick |
| description | La presente invención se refiere a anticuerpos que se unen a alfa sinucleína y fragmentos de la misma capaces de unirse a alfa sinucleína como un monómero y en fibrillas y prevenir la agregación de alfa sinucleína inducida por fibrillas de alfa sinucleína. Los anticuerpos de la presente invención son para uso en el tratamiento de alfa sinucleinopatías, incluyendo la enfermedad de Parkinson.
The present invention relates to antibodies binding alpha synuclein and fragments thereof capable of binding alpha synuclein as a monomer and in fibrils and preventing alpha synuclein aggregation induced by alpha synuclein fibrils. The antibodies of the present invention are for use in the treatment of alpha synucleinopathies, including Parkinson's disease. |
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The present invention relates to antibodies binding alpha synuclein and fragments thereof capable of binding alpha synuclein as a monomer and in fibrils and preventing alpha synuclein aggregation induced by alpha synuclein fibrils. The antibodies of the present invention are for use in the treatment of alpha synucleinopathies, including Parkinson's disease.</description><language>spa</language><subject>CHEMISTRY ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES</subject><creationdate>2020</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20200831&DB=EPODOC&CC=EC&NR=SP20039623A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76289</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20200831&DB=EPODOC&CC=EC&NR=SP20039623A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>ADAMS, Ralph</creatorcontrib><creatorcontrib>LIGHTWOOD, Daniel John</creatorcontrib><creatorcontrib>BAKER, Terence Seward</creatorcontrib><creatorcontrib>DE LICHTERVELDE, Lorenzo</creatorcontrib><creatorcontrib>TYSON, Kerry Louise</creatorcontrib><creatorcontrib>MCMILLAN, David James</creatorcontrib><creatorcontrib>DOWNEY, Patrick</creatorcontrib><title>ANTICUERPOS ANTI ALFA-SINUCLEÍNA</title><description>La presente invención se refiere a anticuerpos que se unen a alfa sinucleína y fragmentos de la misma capaces de unirse a alfa sinucleína como un monómero y en fibrillas y prevenir la agregación de alfa sinucleína inducida por fibrillas de alfa sinucleína. Los anticuerpos de la presente invención son para uso en el tratamiento de alfa sinucleinopatías, incluyendo la enfermedad de Parkinson.
The present invention relates to antibodies binding alpha synuclein and fragments thereof capable of binding alpha synuclein as a monomer and in fibrils and preventing alpha synuclein aggregation induced by alpha synuclein fibrils. The antibodies of the present invention are for use in the treatment of alpha synucleinopathies, including Parkinson's disease.</description><subject>CHEMISTRY</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2020</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZFB09AvxdA51DQrwD1YAsRUcfdwcdYM9_UKdfVwP9_o58jCwpiXmFKfyQmluBiU31xBnD93Ugvz41OKCxOTUvNSSeFfn4AAjAwNjSzMjY0djohQBAK-vI7w</recordid><startdate>20200831</startdate><enddate>20200831</enddate><creator>ADAMS, Ralph</creator><creator>LIGHTWOOD, Daniel John</creator><creator>BAKER, Terence Seward</creator><creator>DE LICHTERVELDE, Lorenzo</creator><creator>TYSON, Kerry Louise</creator><creator>MCMILLAN, David James</creator><creator>DOWNEY, Patrick</creator><scope>EVB</scope></search><sort><creationdate>20200831</creationdate><title>ANTICUERPOS ANTI ALFA-SINUCLEÍNA</title><author>ADAMS, Ralph ; LIGHTWOOD, Daniel John ; BAKER, Terence Seward ; DE LICHTERVELDE, Lorenzo ; TYSON, Kerry Louise ; MCMILLAN, David James ; DOWNEY, Patrick</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_ECSP20039623A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>spa</language><creationdate>2020</creationdate><topic>CHEMISTRY</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><toplevel>online_resources</toplevel><creatorcontrib>ADAMS, Ralph</creatorcontrib><creatorcontrib>LIGHTWOOD, Daniel John</creatorcontrib><creatorcontrib>BAKER, Terence Seward</creatorcontrib><creatorcontrib>DE LICHTERVELDE, Lorenzo</creatorcontrib><creatorcontrib>TYSON, Kerry Louise</creatorcontrib><creatorcontrib>MCMILLAN, David James</creatorcontrib><creatorcontrib>DOWNEY, Patrick</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>ADAMS, Ralph</au><au>LIGHTWOOD, Daniel John</au><au>BAKER, Terence Seward</au><au>DE LICHTERVELDE, Lorenzo</au><au>TYSON, Kerry Louise</au><au>MCMILLAN, David James</au><au>DOWNEY, Patrick</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>ANTICUERPOS ANTI ALFA-SINUCLEÍNA</title><date>2020-08-31</date><risdate>2020</risdate><abstract>La presente invención se refiere a anticuerpos que se unen a alfa sinucleína y fragmentos de la misma capaces de unirse a alfa sinucleína como un monómero y en fibrillas y prevenir la agregación de alfa sinucleína inducida por fibrillas de alfa sinucleína. Los anticuerpos de la presente invención son para uso en el tratamiento de alfa sinucleinopatías, incluyendo la enfermedad de Parkinson.
The present invention relates to antibodies binding alpha synuclein and fragments thereof capable of binding alpha synuclein as a monomer and in fibrils and preventing alpha synuclein aggregation induced by alpha synuclein fibrils. The antibodies of the present invention are for use in the treatment of alpha synucleinopathies, including Parkinson's disease.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY METALLURGY ORGANIC CHEMISTRY PEPTIDES |
| title | ANTICUERPOS ANTI ALFA-SINUCLEÍNA |
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